Rhot1 - ras homolog family member T1 Gene

Rattus norvegicus

Gene ID: 303351 | Gene type: protein coding

About Rhot1

Summary

Predicted to enable GTP binding activity and GTPase activity. Involved in establishment of mitochondrion localization by microtubule attachment; regulation of neurotransmitter secretion; and regulation of organelle transport along microtubule. Colocalizes with mitochondrion. Orthologous to human RHOT1 (Ras homolog family member T1). [provided by Alliance of Genome Resources, Apr 2022]

Rhot1 Products(1)

mRNA	Protein	Name
NM_001107026.2	NP_001100496.1	mitochondrial Rho GTPase 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	19103291	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in establishment of mitochondrion localization by microtubule attachment	IMP IMP: Inferred from mutant phenotype	24302729	RGD
involved in regulation of neurotransmitter secretion	IMP IMP: Inferred from mutant phenotype	24302729	RGD
involved in regulation of organelle transport along microtubule	IMP IMP: Inferred from mutant phenotype	24302729	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

mitochondrial Rho GTPase 1

ras homolog gene family, member T1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11957	RHOT1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rhot1	NCBI	NCBI:55288

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