Cenpj - centromere protein J Gene

Predicted to enable several functions, including gamma-tubulin binding activity; identical protein binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including cilium assembly; microtubule Cytoskeleton organization; and positive regulation of centriole elongation. Predicted to act upstream of or within several processes, including astral microtubule nucleation; organelle assembly; and positive regulation of non-motile cilium assembly. Predicted to be located in several cellular components, including ciliary basal body; nucleoplasm; and plasma membrane. Predicted to be active in centriole; centrosome; and nucleus. Human ortholog(s) of this gene implicated in Seckel syndrome 4; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 6. Orthologous to human CENPJ (centromere protein J). [provided by Alliance of Genome Resources, Apr 2022]