2. Gene
  3. Nisch - nischarin Gene

Nisch - nischarin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as I-1; I1R; IR1

Gene ID: 306255 | Gene type: protein coding

About Nisch

Summary

Predicted to enable identical protein binding activity; Integrin binding activity; and protein kinase binding activity. Involved in several processes, including glucose metabolic process; norepinephrine secretion; and regulation of GABAergic synaptic transmission. Predicted to be located in several cellular components, including intercellular bridge; microtubule cytoskeleton; and nucleoplasm. Predicted to be active in cytoplasm. Used to study hypertension. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human NISCH (nischarin). [provided by Alliance of Genome Resources, Apr 2022]

Nisch Products(2)

mRNA Protein Name
NM_001376918.1 NP_001363847.1 nischarin isoform 1
NM_001409024.1 NP_001395953.1 nischarin isoform 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in glucose metabolic process IMP
IMP: Inferred from mutant phenotype
15028595 RGD
involved in norepinephrine secretion IMP
IMP: Inferred from mutant phenotype
15028598 RGD
involved in regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
14975931 RGD
involved in regulation of synaptic transmission, GABAergic IMP
IMP: Inferred from mutant phenotype
16467528 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nischarin

I-1 receptor candidate protein

imidazoline receptor 1

imidazoline receptor I-1

imidazoline-1 receptor

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09309 NISCH Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nisch NCBI NCBI:11188