Ank1 - ankyrin 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 306570

Summary

Predicted to enable several functions, including enzyme binding activity; spectrin binding activity; and transmembrane transporter binding activity. Involved in positive regulation of organelle organization. Located in several cellular components, including axolemma; sarcolemma; and sarcomere. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1). [provided by Alliance of Genome Resources, Apr 2022]

Ank1 Products (7)

mRNA Protein Name
NM_001395562.1 NP_001382491.1 ankyrin-1 isoform 1
NM_001395563.1 NP_001382492.1 ankyrin-1 isoform 2
NM_001395564.1 NP_001382493.1 ankyrin-1 isoform 3
NM_001395565.1 NP_001382494.1 ankyrin-1 isoform 4
NM_001395566.1 NP_001382495.1 ankyrin-1 isoform 5
NM_001395567.1 NP_001382496.1 ankyrin-1 isoform 6
NM_001395568.1 NP_001382497.1 ankyrin-1 isoform 7

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12631729 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of organelle organization IMP
IMP: Inferred from mutant phenotype
22045734 RGD
Cellular Component GO Annotation Evidence References Source
located in A band IDA
IDA: Inferred from direct assay
9664041 RGD
located in M band IDA
IDA: Inferred from direct assay
9024692 RGD
located in Z disc IDA
IDA: Inferred from direct assay
9024692 RGD
located in axolemma IDA
IDA: Inferred from direct assay
2139035 RGD
located in postsynaptic membrane IDA
IDA: Inferred from direct assay
9664041 RGD
located in sarcolemma IDA
IDA: Inferred from direct assay
9024692 RGD
located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
9024692 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ankyrin-1

  • ankyrin 1, erythrocytic

  • ankyrin 1, erythroid

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00735 ANKS1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00699 ANK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00736 ANKS1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ank1 NCBI NCBI:286
Mus musculus Ank1 NCBI NCBI:11733