1. Gene
  2. Irx2 - iroquois homeobox 2 Gene

Irx2 - iroquois homeobox 2 Gene

Rattus norvegicus
Gene ID: 306657 | Gene type: protein coding

About Irx2

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell development; negative regulation of transcription by RNA polymerase II; and neuron differentiation. Predicted to act upstream of or within proximal/distal pattern formation involved in metanephric nephron development and specification of loop of Henle identity. Predicted to be active in nucleus. Orthologous to human IRX2 (iroquois homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Irx2 Products(1)

mRNA Protein Name
NM_001039505.3 NP_001034594.1 iroquois-class homeodomain protein IRX-2
Protein Preferred Names Protein Names

iroquois-class homeodomain protein IRX-2

Iroquois related homeobox 2

Iroquois related homeobox 5

Orthologs Information

Species Symbol Source ID
Homo sapiens Irx2 NCBI NCBI:153572