PHACTR1 - Phactr1 phosphatase and actin regulator 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 306844

Summary

Enables protein Phosphatase 1 binding activity. Involved in regulation of phosphorylation. Located in synapse. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 70. Orthologous to human PHACTR1 (Phosphatase and actin regulator 1). [provided by Alliance of Genome Resources, Apr 2022]

PHACTR1 Products (1)

mRNA Protein Name
NM_214457.2 NP_999622.2 phosphatase and actin regulator 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein phosphatase 1 binding IDA
IDA: Inferred from direct assay
15107502 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to mechanical stimulus IEP
IEP: Inferred from expression pattern
26098115 RGD
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
26098115 RGD
involved in regulation of modification of postsynaptic structure IDA
IDA: Inferred from direct assay
32975518 RGD
involved in regulation of modification of postsynaptic structure IMP
IMP: Inferred from mutant phenotype
32975518 RGD
involved in regulation of phosphorylation IDA
IDA: Inferred from direct assay
15107502 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
26098115 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
15107502 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
15107502 RGD
located in nucleus IDA
IDA: Inferred from direct assay
26098115 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
15107502 RGD
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
15107502 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatase and actin regulator 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10402 PHACTR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PHACTR1 NCBI NCBI:221692