PHACTR1 - Phactr1 phosphatase and actin regulator 1 Gene

Rattus norvegicus

Gene ID: 306844 | Gene type: protein coding

About PHACTR1

Summary

Enables protein Phosphatase 1 binding activity. Involved in regulation of phosphorylation. Located in synapse. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 70. Orthologous to human PHACTR1 (Phosphatase and actin regulator 1). [provided by Alliance of Genome Resources, Apr 2022]

PHACTR1 Products(1)

mRNA	Protein	Name
NM_214457.2	NP_999622.2	phosphatase and actin regulator 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein phosphatase 1 binding	IDA IDA: Inferred from direct assay	15107502	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to mechanical stimulus	IEP IEP: Inferred from expression pattern	26098115	RGD
involved in positive regulation of gene expression	IMP IMP: Inferred from mutant phenotype	26098115	RGD
involved in regulation of modification of postsynaptic structure	IDA IDA: Inferred from direct assay	32975518	RGD
involved in regulation of modification of postsynaptic structure	IMP IMP: Inferred from mutant phenotype	32975518	RGD
involved in regulation of phosphorylation	IDA IDA: Inferred from direct assay	15107502	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	26098115	RGD
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	15107502	RGD
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	15107502	RGD
located in nucleus	IDA IDA: Inferred from direct assay	26098115	RGD
is active in postsynapse	IDA IDA: Inferred from direct assay	15107502	RGD
is active in postsynapse	IMP IMP: Inferred from mutant phenotype	15107502	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

phosphatase and actin regulator 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10402	PHACTR1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	PHACTR1	NCBI	NCBI:221692

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