Tomm40 - translocase of outer mitochondrial membrane 40 Gene

Also Known as OM38; TOM40

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 308416

Summary

Enables cation channel activity; preprotein binding activity; and protein transmembrane transporter activity. Involved in positive regulation of apoptotic process; protein insertion into mitochondrial membrane; and protein targeting to mitochondrion. Located in mitochondrial outer membrane. Is integral component of mitochondrial outer membrane. Part of mitochondrial outer membrane translocase complex. Human ortholog(s) of this gene implicated in cerebral infarction. Orthologous to human TOMM40 (translocase of outer mitochondrial membrane 40). [provided by Alliance of Genome Resources, Apr 2022]

Tomm40 Products (1)

mRNA Protein Name
NM_212520.2 NP_997685.2 mitochondrial import receptor subunit TOM40 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables monoatomic cation channel activity IDA
IDA: Inferred from direct assay
15347672 RGD
enables preprotein binding IDA
IDA: Inferred from direct assay
15347672 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
19401463 RGD
enables protein transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
18687331 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
18687331 RGD
involved in protein insertion into mitochondrial membrane IMP
IMP: Inferred from mutant phenotype
18687331 RGD
involved in protein targeting to mitochondrion IDA
IDA: Inferred from direct assay
10980201 RGD
involved in protein targeting to mitochondrion IMP
IMP: Inferred from mutant phenotype
15347672 RGD
Cellular Component GO Annotation Evidence References Source
located in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
10980201 RGD
part of mitochondrial outer membrane translocase complex IDA
IDA: Inferred from direct assay
10980201 RGD
located in mitochondrion IDA
IDA: Inferred from direct assay
10980201 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial import receptor subunit TOM40 homolog

  • mitochondrial outer membrane protein of 38 kDa

  • outer membrane protein 38 kDa

  • translocase of outer membrane 40 kDa subunit homolog

  • translocase of outer mitochondrial membrane 40 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14882 TOMM40 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14883 TOMM40L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tomm40 NCBI NCBI:10452