2. Gene
  3. Ndn - necdin, MAGE family member Gene

Ndn - necdin, MAGE family member Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 308690 | Gene type: protein coding

About Ndn

Summary

Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; gamma-tubulin binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including nervous system development; neurotrophin Trk Receptor signaling pathway; and regulation of transcription, DNA-templated. Located in cytoplasm. Human ortholog(s) of this gene implicated in Prader-Willi syndrome. Orthologous to human NDN (necdin, MAGE family member). [provided by Alliance of Genome Resources, Apr 2022]

Ndn Products(1)

mRNA Protein Name
NM_001008558.2 NP_001008558.2 necdin
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12414813 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

necdin

necdin homolog

necdin, melanoma antigen (MAGE) family member

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09110 NDN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ndn NCBI NCBI:4692