Dennd5a - DENN domain containing 5A Gene

Also Known as Rab6ip1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 308942

Summary

Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in negative regulation of neuron projection development. Predicted to be located in trans-Golgi network. Predicted to be part of retromer complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 49. Orthologous to human DENND5A (DENN domain containing 5A). [provided by Alliance of Genome Resources, Apr 2022]

Dennd5a Products (1)

mRNA Protein Name
NM_001107546.2 NP_001101016.2 DENN domain-containing protein 5A

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
27866705 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DENN domain-containing protein 5A

  • DENN/MADD domain containing 5A

  • Rab6 interacting protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03690 DENND5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dennd5a NCBI NCBI:23258