INPP5F - Inpp5f inositol polyphosphate-5-phosphatase F Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 309008

Summary

Predicted to enable Phosphatase activity and protein homodimerization activity. Involved in negative regulation of peptidyl-serine phosphorylation. Acts upstream of or within regulation of protein kinase B signaling. Predicted to be located in several cellular components, including dendrite; neuronal cell body; and recycling endosome. Predicted to be active in clathrin-coated endocytic vesicle and early endosome. Predicted to colocalize with clathrin-coated pit. Orthologous to human INPP5F (inositol polyphosphate-5-phosphatase F). [provided by Alliance of Genome Resources, Apr 2022]

INPP5F Products (1)

mRNA Protein Name
NM_001107554.1 NP_001101024.2 phosphatidylinositide phosphatase SAC2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of peptidyl-serine phosphorylation IMP
IMP: Inferred from mutant phenotype
26908121 RGD
acts upstream of or within regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
17322895 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylinositide phosphatase SAC2

  • phosphatidylinositide phosphatase SAC2-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06831 INPP5F Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09746 OCRL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens INPP5F NCBI NCBI:22876