2. Gene
  3. Nkx6-2 - NK6 homeobox 2 Gene

Nkx6-2 - NK6 homeobox 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 309095 | Gene type: protein coding

About Nkx6-2

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation; regulation of myelination; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; neurogenesis; and neuromuscular process controlling balance. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in spastic ataxia 8. Orthologous to human NKX6-2 (NK6 homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Nkx6-2 Products(2)

mRNA Protein Name
NM_001107558.2 NP_001101028.1 homeobox protein Nkx-6.2
NM_001107558.2 NP_001101028.1 homeobox protein Nkx-6.2
Protein Preferred Names Protein Names

homeobox protein Nkx-6.2

NK6 transcription factor related, locus 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09336 NKX6-2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nkx6-2 NCBI NCBI:84504