Fan1 - FANCD2 and FANCI associated nuclease 1 Gene

Rattus norvegicus

Also known as Mtmr15; RGD1566323

Gene ID: 309256 | Gene type: protein coding

About Fan1

Summary

Predicted to enable flap-structured DNA binding activity; nuclease activity; and ubiquitin-dependent protein binding activity. Predicted to be involved in double-strand break repair via homologous recombination; interstrand cross-link repair; and nucleotide-excision repair, DNA incision. Predicted to be located in cytosol; intercellular bridge; and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in karyomegalic interstitial nephritis. Orthologous to human FAN1 (FANCD2 and FANCI associated nuclease 1). [provided by Alliance of Genome Resources, Apr 2022]

Fan1 Products(1)

mRNA	Protein	Name
NM_001191633.1	NP_001178562.1	fanconi-associated nuclease 1

Protein Preferred Names

Protein Names

fanconi-associated nuclease 1

FANCD2/FANCI-associated nuclease 1	coiled-coil domain-containing protein MTMR15
myotubularin related protein 15

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05119	FSCN1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS04731	FAN1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS19004	Fscn1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22166	Fan1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Fan1	NCBI	NCBI:22909

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