Cngb3 - cyclic nucleotide gated channel beta 3 Gene

Mus musculus

Also known as CNG6; CCNC2; Cngbeta2

Gene ID: 30952 | Gene type: protein coding

About Cngb3

Summary

Enables intracellular cGMP-activated cation channel activity. Predicted to be involved in cation transport. Predicted to act upstream of or within ion transport. Located in photoreceptor outer segment. Used to study achromatopsia 3. Human ortholog(s) of this gene implicated in achromatopsia 3 and color blindness. Orthologous to human CNGB3 (cyclic nucleotide gated channel subunit beta 3). [provided by Alliance of Genome Resources, Apr 2022]

Cngb3 Products(1)

mRNA	Protein	Name
NM_013927.2	NP_038955.1	cyclic nucleotide-gated cation channel beta-3

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables intracellularly cGMP-activated cation channel activity	IPI IPI: Inferred from physical interaction	10662822	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	10662822	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in photoreceptor outer segment	IDA IDA: Inferred from direct assay	15634774	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cyclic nucleotide-gated cation channel beta-3

CNG channel beta-3	cone photoreceptor cGMP-gated channel subunit beta
cyclic nucleotide gated channel beta 6	cyclic nucleotide-gated cation channel modulatory subunit
cyclic nucleotide-gated channel subunit CNG6

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02884	CNGB3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cngb3	NCBI	NCBI:54714

Name
Email *

	Sorry, but the email address you supplied was invalid.