Cngb3 - cyclic nucleotide gated channel beta 3 Gene

Also Known as CNG6; CCNC2; Cngbeta2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 30952

Summary

Enables intracellular cGMP-activated cation channel activity. Predicted to be involved in cation transport. Predicted to act upstream of or within ion transport. Located in photoreceptor outer segment. Used to study achromatopsia 3. Human ortholog(s) of this gene implicated in achromatopsia 3 and color blindness. Orthologous to human CNGB3 (cyclic nucleotide gated channel subunit beta 3). [provided by Alliance of Genome Resources, Apr 2022]

Cngb3 Products (1)

mRNA Protein Name
NM_013927.2 NP_038955.1 cyclic nucleotide-gated cation channel beta-3

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables intracellularly cGMP-activated cation channel activity IPI
IPI: Inferred from physical interaction
10662822 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10662822 MGI
Cellular Component GO Annotation Evidence References Source
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
15634774 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclic nucleotide-gated cation channel beta-3

  • CNG channel beta-3

  • cone photoreceptor cGMP-gated channel subunit beta

  • cyclic nucleotide gated channel beta 6

  • cyclic nucleotide-gated cation channel modulatory subunit

  • cyclic nucleotide-gated channel subunit CNG6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02884 CNGB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cngb3 NCBI NCBI:54714