Phc1 - polyhomeotic homolog 1 Gene

About Phc1

Summary

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in histone ubiquitination and negative regulation of transcription, DNA-templated. Predicted to act upstream of or within cellular response to Leukemia Inhibitory Factor and cellular response to retinoic acid. Predicted to be located in nuclear body and sex chromatin. Predicted to be part of PRC1 complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 11. Orthologous to human PHC1 (polyhomeotic homolog 1). [provided by Alliance of Genome Resources, Apr 2022]