2. Gene
  3. Prex2 - phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 Gene

Prex2 - phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Depdc2

Gene ID: 312912 | Gene type: protein coding

About Prex2

Summary

Predicted to enable GTPase activator activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within adult locomotory behavior; dendrite morphogenesis; and phosphatidylinositol 3-kinase signaling. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Klatskin's tumor. Orthologous to human PREX2 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Prex2 Products(1)

mRNA Protein Name
NM_001393795.1 NP_001380724.1 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
Protein Preferred Names Protein Names

phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein

DEP domain containing 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11086 PREX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prex2 NCBI NCBI:80243