2. Gene
  3. C8b - complement C8 beta chain Gene

C8b - complement C8 beta chain Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 313421 | Gene type: protein coding

About C8b

Summary

Predicted to be involved in complement activation, alternative pathway; complement activation, classical pathway; and cytolysis. Located in extracellular space. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in type II Complement Component 8 deficiency. Orthologous to human C8B (complement C8 beta chain). [provided by Alliance of Genome Resources, Apr 2022]

C8b Products(1)

mRNA Protein Name
NM_001191759.1 NP_001178688.1 complement component C8 beta chain precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
3312411 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular region IDA
IDA: Inferred from direct assay
3312411 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
3312411 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

complement component C8 beta chain

complement component 8 subunit beta

complement component 8, beta polypeptide

complement component 8, beta subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01756 C8B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens C8b NCBI NCBI:732