Shroom4 - shroom family member 4 Gene

Also Known as RGD1563434

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 317391

Summary

Predicted to enable actin filament binding activity and Myosin II binding activity. Predicted to be involved in actin filament organization; brain development; and cognition. Predicted to be located in several cellular components, including actin cytoskeleton; basal plasma membrane; and focal adhesion. Predicted to be active in several cellular components, including adherens junction; apical junction complex; and apical plasma membrane. Human ortholog(s) of this gene implicated in Stocco Dos Santos type X-linked intellectual disability. Orthologous to human SHROOM4 (shroom family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Shroom4 Products (1)

mRNA Protein Name
NM_001191730.1 NP_001178659.1 protein Shroom4

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
28262662 RGD
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
28262662 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
28262662 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
28262662 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
28262662 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
28262662 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Shroom4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12887 SHROOM4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Shroom4 NCBI NCBI:57477