Slc24a5 - solute carrier family 24, member 5 Gene

Also Known as JSX; NCX5; Oca6; NCKX5; F630045L20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 317750

Summary

Enables calcium ion transmembrane transporter activity. Involved in calcium ion import. Acts upstream of or within negative regulation of melanin biosynthetic process. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Predicted to be active in trans-Golgi network. Is expressed in several structures, including brain; ear; gonad; spleen; and submandibular gland. Used to study ocular albinism. Human ortholog(s) of this gene implicated in oculocutaneous albinism type VI. Orthologous to human SLC24A5 (solute carrier family 24 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc24a5 Products (1)

mRNA Protein Name
NM_175034.3 NP_778199.2 sodium/potassium/calcium exchanger 5 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables calcium ion transmembrane transporter activity IDA
IDA: Inferred from direct assay
27093457 MGI
Biological Process GO Annotation Evidence References Source
involved in calcium ion import IDA
IDA: Inferred from direct assay
27093457 MGI
acts upstream of melanin biosynthetic process IMP
IMP: Inferred from mutant phenotype
18166528 MGI
acts upstream of or within negative regulation of melanin biosynthetic process IMP
IMP: Inferred from mutant phenotype
18166528 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium/potassium/calcium exchanger 5

  • K-independent Na+/Ca2+ exchanger JSX

  • Na(+)/K(+)/Ca(2+)-exchange protein 5

  • Na-Ca exchanger 5

  • sodium/potassion/calcium exchanger 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13088 SLC24A5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc24a5 NCBI NCBI:283652