GADL1 - glutamate decarboxylase like 1 Gene

Also Known as ADC; CSADC; HuADC; HuCSADC

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 339896

About GADL1

Cytogenetic location: 3p24.1-p23 Genomic coordinates (GRCh38): 3:30,726,197-30,894,661 (from NCBI)

This gene has 3 transcripts (splice variants), 193 orthologues and 7 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable aspartate 1-decarboxylase activity; pyridoxal phosphate binding activity; and sulfinoalanine decarboxylase activity. Predicted to be involved in carboxylic acid metabolic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

GADL1 Products (1)

mRNA Protein Name
NM_207359.3 NP_997242.2 acidic amino acid decarboxylase GADL1

GADL1 Protein Structure

Pyridoxal_deC

Pyridoxal_deC: Pyridoxal-dependent decarboxylase conserved domain (77 - 444)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 521 a.a.
Protein Preferred Names Protein Names

acidic amino acid decarboxylase GADL1

  • aspartate 1-decarboxylase

Related Diseases

Diseases Alias
Bainbridge-Ropers Syndrome

  • BRPS

  • Severe Feeding Difficulties-Failure To Thrive-Microcephaly Due To Asxl3 Deficiency Syndrome

  • Asxl3-Related Disorder
Bipolar I Disorder

  • Manic Depression Nos

  • Manic-Depressive Illness

  • Bipolar Disorder Nos
Bipolar Disorder

  • Bipolar Depression

  • Manic Disorder

  • Depression, Bipolar

  • Bipolar Disorder Manic Phase

  • Depressive-Manic Psych.

  • Manic Bipolar Affective Disorder

  • Manic Bipolar I Disorder

  • Manic Depression

  • Manic Depressive Disorder

  • Mixed Bipolar Disorder

  • Bipolar Affective Disorder

  • Bipolar Affective Psychosis

  • Bipolar Spectrum Disorder

  • Manic Depressive Illness

  • Depression Bipolar

  • Bipolar Disorder, Mixed

  • Major Affective Disorder

  • Major Affective Disorder 1

  • Major Affective Disorder 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05232 GADL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GADL1 RGD RGD:1565145
Macaca mulatta GADL1 VGNC VGNC:72796
Felis catus GADL1 VGNC VGNC:62433
Canis familiaris GADL1 VGNC VGNC:41073
Mus musculus GADL1 MGD MGI:1920998
Bos taurus GADL1 VGNC VGNC:29210
Others GADL1 NCBI