IFNA21 - interferon alpha 21 Gene

Also Known as LeIF F; leIF-F; IFN-alphaI

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3452

About IFNA21

Cytogenetic location: 9p21.3 Genomic coordinates (GRCh38): 9:21,165,637-21,166,660 (from NCBI)

This gene has 1 transcript (splice variant), 588 orthologues and 16 paralogues.

Summary

This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral Infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the Antiviral response to rubella virus. [provided by RefSeq, Sep 2011]

IFNA21 Products (1)

mRNA Protein Name
NM_002175.2 NP_002166.2 interferon alpha-21 precursor
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IFNA21 Protein Structure

Interferon

Interferon: Interferon alpha/beta domain (26 - 187)

  • 0
  • 100
  • 189 a.a.
Protein Preferred Names Protein Names

interferon alpha-21

  • IFN-alpha-21

Related Diseases

Diseases Alias
Rubella
  • German Measles

  • Three Day Measles

  • Rubella Nos

Multisystem Inflammatory Syndrome In Children
  • Mis-C

  • Multisystem Inflammatory Disorder In Children And Adolescents

  • Paediatric Inflammatory Multisystemic Syndrome

  • Mic

Melanoma, Cutaneous Malignant 1
  • Familial Melanoma

  • Melanoma, Cutaneous Malignant, Susceptibility To, 1

  • Melanoma, Malignant

  • CMM1

  • Melanoma, Cutaneous Malignant

  • Cmm

  • Familial Atypical Mole-Malignant Melanoma Syndrome

  • Fammm

  • Melanoma, Familial

  • Mlm

  • Dysplastic Nevus Syndrome, Hereditary

  • Dns

  • B-K Mole Syndrome

  • Melanoma, Cutaneous Malignant, 1

  • Malignant Melanoma, Cutaneous

  • Melanoma, Cutaneous, Malignant, Susceptibility To, Type 1

  • Dysplastic Nevus Syndrome

  • Cutaneous Melanoma

  • Familial Atypical Mole Melanoma Syndrome

  • Hereditary Melanoma

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Others IFNA21 NCBI