Opn5 - opsin 5 Gene

Also Known as PGR12; Gpr136; TMEM13; Neuropsin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 353344

Summary

Enables 11-cis retinal binding activity and G protein-coupled photoreceptor activity. Involved in entrainment of circadian clock by photoperiod; hyaloid vascular plexus regression; and phototransduction, UV. Predicted to be located in cytoplasm and plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human OPN5 (opsin 5). [provided by Alliance of Genome Resources, Apr 2022]

Opn5 Products (1)

mRNA Protein Name
NM_181753.4 NP_861418.2 opsin-5

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables 11-cis retinal binding IDA
IDA: Inferred from direct assay
24403072 MGI
enables 11-cis retinal binding IMP
IMP: Inferred from mutant phenotype
22043319 MGI
enables G protein-coupled photoreceptor activity IMP
IMP: Inferred from mutant phenotype
22043319 MGI
enables G protein-coupled receptor activity IDA
IDA: Inferred from direct assay
24403072 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to light stimulus IMP
IMP: Inferred from mutant phenotype
31607531 MGI
involved in entrainment of circadian clock by photoperiod IMP
IMP: Inferred from mutant phenotype
26392540 MGI
involved in hyaloid vascular plexus regression IMP
IMP: Inferred from mutant phenotype
30936473 MGI
involved in phototransduction IMP
IMP: Inferred from mutant phenotype
30936473 MGI
involved in phototransduction, UV IMP
IMP: Inferred from mutant phenotype
22043319 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

opsin-5

  • G protein-coupled receptor 136

  • G-protein coupled receptor PGR12

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09800 OPN5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Opn5 NCBI NCBI:221391