Nfatc3 - nuclear factor of activated T-cells 3 Gene

Also Known as NFAT4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361400

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in positive regulation of transcription, DNA-templated. Located in cytosol and nucleus. Orthologous to human NFATC3 (nuclear factor of activated T cells 3). [provided by Alliance of Genome Resources, Apr 2022]

Nfatc3 Products (1)

mRNA Protein Name
NM_001108447.2 NP_001101917.1 nuclear factor of activated T-cells, cytoplasmic 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
30980393 RGD
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
19538478 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
15016802 RGD
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
30980393 RGD
involved in positive regulation of cardiac muscle hypertrophy IMP
IMP: Inferred from mutant phenotype
30980393 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
19538478 RGD
involved in protein import into nucleus IDA
IDA: Inferred from direct assay
21273244 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19538478 RGD
located in nucleus IDA
IDA: Inferred from direct assay
19538478 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear factor of activated T-cells, cytoplasmic 3

  • T cell transcription factor NFAT4

  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N1353 Rhamnocitrin Inhibitor 99.67% Unkown
HY-P10889 CNI103 Inhibitor 99.56% Unkown
HY-RS09241 NFATC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfatc3 NCBI NCBI:4775