2. Gene
  3. Cyp2r1 - cytochrome P450, family 2, subfamily r, polypeptide 1 Gene

Cyp2r1 - cytochrome P450, family 2, subfamily r, polypeptide 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 361631 | Gene type: protein coding

About Cyp2r1

Summary

Predicted to enable several functions, including heme binding activity; monooxygenase activity; and protein homodimerization activity. Involved in response to cesium ion and response to ionizing radiation. Located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and vitamin D-dependent rickets type 1B. Orthologous to human CYP2R1 (Cytochrome P450 family 2 subfamily R member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp2r1 Products(2)

mRNA Protein Name
NM_001108499.1 NP_001101969.1 vitamin D 25-hydroxylase isoform 2
NM_001401627.1 NP_001388556.1 vitamin D 25-hydroxylase isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to cesium ion IEP
IEP: Inferred from expression pattern
16806633 RGD
involved in response to ionizing radiation IEP
IEP: Inferred from expression pattern
16806633 RGD
involved in response to metal ion IEP
IEP: Inferred from expression pattern
16502312 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vitamin D 25-hydroxylase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03466 CYP2R1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyp2r1 NCBI NCBI:120227