Ndufs7 - NADH:ubiquinone oxidoreductase core subunit S7 Gene

Rattus norvegicus

Gene ID: 362837 | Gene type: protein coding

About Ndufs7

Summary

Enables protease binding activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Located in neuron projection; neuronal cell body; and synaptic membrane. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 3. Orthologous to human NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7). [provided by Alliance of Genome Resources, Apr 2022]

Ndufs7 Products(1)

mRNA	Protein	Name
NM_001008525.1	NP_001008525.1	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protease binding	IPI IPI: Inferred from physical interaction	22535952	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in neuronal cell body	IDA IDA: Inferred from direct assay	22535952	RGD
located in synaptic membrane	IDA IDA: Inferred from direct assay	22521230	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

NADH dehydrogenase (ubiquinone) Fe-S protein 7

NADH-ubiquinone oxidoreductase Fe-S protein 7

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-182242	AGB-374	Inhibitor	/	Unkown
HY-RS09163	NDUFS7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ndufs7	NCBI	NCBI:374291

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