MIR15A - microRNA 15a Gene

Also Known as MIRN15A; mir-15a; miRNA15A; hsa-mir-15a

Species: Homo sapiens

Gene Type: ncRNA

Gene ID: 406948

About MIR15A

Cytogenetic location: 13q14.2 Genomic coordinates (GRCh38): 13:50,049,119-50,049,201 (from NCBI)

This gene has 1 transcript (splice variant), 81 orthologues and 4 paralogues.

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables mRNA 3'-UTR binding	IDA IDA: Inferred from direct assay	26440600	GOA
enables mRNA base-pairing translational repressor activity	IDA IDA: Inferred from direct assay	15131085	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in activation of cysteine-type endopeptidase activity involved in apoptotic process	IDA IDA: Inferred from direct assay	23353574	GOA
involved in cellular response to glucose stimulus	IDA IDA: Inferred from direct assay	30365148	GOA
involved in miRNA-mediated gene silencing by inhibition of translation	IDA IDA: Inferred from direct assay	23233752	GOA
involved in miRNA-mediated post-transcriptional gene silencing	IDA IDA: Inferred from direct assay	15131085	GOA
involved in negative regulation of G1/S transition of mitotic cell cycle	IDA IDA: Inferred from direct assay	21454377	GOA
involved in negative regulation of G1/S transition of mitotic cell cycle	IMP IMP: Inferred from mutant phenotype	23867820	GOA
involved in negative regulation of NF-kappaB transcription factor activity	IDA IDA: Inferred from direct assay	30365148	GOA
involved in negative regulation of angiogenesis	IDA IDA: Inferred from direct assay	23233752	GOA
involved in negative regulation of angiogenesis	IMP IMP: Inferred from mutant phenotype	23867820	GOA
involved in negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	IDA IDA: Inferred from direct assay	22692216	GOA
involved in negative regulation of canonical NF-kappaB signal transduction	IDA IDA: Inferred from direct assay	23487264	GOA
involved in negative regulation of cell chemotaxis to fibroblast growth factor	IDA IDA: Inferred from direct assay	23233752	GOA
involved in negative regulation of cell migration involved in sprouting angiogenesis	IDA IDA: Inferred from direct assay	22692216	GOA
involved in negative regulation of cell population proliferation	IGI IGI: Inferred from genetic interaction	22139073	GOA
involved in negative regulation of cyclin-dependent protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	27343180	GOA
involved in negative regulation of inflammatory response	IDA IDA: Inferred from direct assay	30365148	GOA
involved in negative regulation of peptidyl-threonine phosphorylation	IDA IDA: Inferred from direct assay	27343180	GOA
involved in negative regulation of vascular associated smooth muscle cell migration	IDA IDA: Inferred from direct assay	23233752	GOA
involved in negative regulation of vascular associated smooth muscle cell proliferation	IDA IDA: Inferred from direct assay	23233752	GOA
involved in positive regulation of apoptotic process	IDA IDA: Inferred from direct assay	25261849	GOA
involved in positive regulation of intrinsic apoptotic signaling pathway	IGI IGI: Inferred from genetic interaction	16166262	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in extracellular exosome	IDA IDA: Inferred from direct assay	23233752	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Diseases

Diseases	Alias
Pituitary Adenoma	Adenoma Of The Pituitary Gland Pituitary Adenomas Adenoma, Pituitary Pituitary Gland Adenoma Pituitary Neoplasms
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Myeloma, Multiple	Multiple Myeloma Plasma Cell Myeloma Kahler Disease Myelomatosis Medullary Plasmacytoma Multiple Myeloma, Resistance To Myeloma Plasma Cell Dyscrasia Kahler'S Disease Multiple Myeloma, Susceptibility To Myeloma - Multiple Kahler-Bozzolo Disease Plasma Cell Myelomas MM Plasma Cell Neoplasm Primary Systemic Amyloidosis Primary Amyloidosis Immunoglobulin Deposition Disease Plasmacytic Myeloma Multiple Myelomata Multiple Myeloma Nos Multiple Myeloma Without Mention Of Remission Monostotic Plasma Cell Myeloma Mm - [Multiple Myeloma]
Polycystic Liver Disease	Autosomal Dominant Polycystic Liver Disease Isolated Polycystic Liver Disease Pcld Congenital Cystic Liver Disease Congenital Hepatic Cyst Fibrocystic Liver Disease Isolated Autosomal Dominant Polycystic Liver Disease Adpcld Liver Disease, Polycystic Multiple Cysts Of Liver Pld - [Polycystic Liver Disease] Polycystic Liver Disorder Polycystic Liver Congenital Polycystic Disease Of Liver Congenital Polycystic Liver Disease
Polycystic Kidney Disease	Polycystic Kidney Diseases Pkd Polycystic Renal Disease Kidney Disease, Polycystic Polycystic Kidney, Autosomal Dominant
Acute Promyelocytic Leukemia	Leukemia, Acute Promyelocytic Acute Myeloblastic Leukemia Type 3 Aml M3 APL Leukemia, Acute Promyelocytic, Somatic Aml With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Apml Acute Myeloblastic Leukemia 3 Acute Myeloid Leukemia With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Acute Myeloblastic Leukaemia Type 3 Acute Myeloid Leukaemia M3 Acute Myeloid Leukemia M3 Acute Promyelocytic Leukaemia M3 Anll Myeloid Leukemia, Acute, M3 Leukemia Promyelocytic Acute Leukemia, Promyelocytic, Acute Leukemia, Acute, Promyelocytic
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Squamous Cell Carcinoma, Head And Neck	Squamous Cell Carcinoma Of The Head And Neck HNSCC Head And Neck Squamous Cell Carcinoma Squamous Cell Carcinoma Of Lip Squamous Cell Carcinoma, Head And Neck, Somatic Carcinoma Of The Head And Neck Squamous Cell Carcinomas Of Head And Neck Scchn Squamous Cell Carcinoma Of The Hypopharynx Squamous Cell Carcinoma Of The Oropharynx Squamous Cell Carcinoma Of Salivary Glands Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses Squamous Cell Carcinoma Of The Oral Cavity Squamous Cell Carcinoma Of The Lip Carcinoma, Squamous Cell Of Head And Neck Lip Squamous Cell Carcinoma Carcinoma, Squamous Cell, Head And Neck Salivary Gland Squamous Cell Carcinoma Cancer Of Head And Neck Squamous Cell Carcinoma Of Oropharynx Nos
Kidney Cancer	Renal Cancer Renal Carcinoma Kidney Neoplasm Malignant Neoplasm Of Kidney Except Pelvis Malignant Tumour Of Kidney Kidney Neoplasms Cancer, Kidney Cancer, Renal Malignant Neoplasm Of Kidney Renal Cell Carcinoma
Autism Spectrum Disorder	Asd Autism Spectrum Disorders Autistic Continuum Pervasive Developmental Disorder Pervasive Development Disorder Autistic Behavior Autistic Disorder Autistic Autistic Disorder Of Childhood Onset Infantile Autism Childhood Autism Kanner Syndrome Pervasive Developmental Delay Nos Pervasive Developmental Disorder, Not Otherwise Specified
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Glioma
Schizophrenia	SCZD Schizophrenia With Or Without An Affective Disorder Schizophrenia 12 Schizophrenia, Susceptibility To Schizophrenia-1 Dementia Praecox Schizophrenia 1
Melanoma	Malignant Melanoma Cutaneous Melanoma Naevocarcinoma Malignant Melanomas
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Carcinoma, Hepatocellular Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma	Cll/Sll B-Cell Lymphocytic Leukemia/Small Lymphocytic Lymphoma Icdo:9823/3 Chronic Lymphocytic Leukaemia Of B-Cell Type Without Mention Of Remission Small Cell B-Cell Lymphoma
Lymphatic System Cancer
Lymphatic System Disease	Lymphatic Diseases Adenopathy Lymphatic Disease Disease Of Lympoid System Disorder Of Lymph Node And Lymphatics Disorder Of Lymphatic System Disorder Of Lymphoid System Lymphangiopathy Lymphatic Disorder Lympoid System Disease Abnormality Of The Lymphatic System
Tongue Disease	Abnormality Of The Tongue Tongue Diseases Tongue Disorders Disorder Of Tongue Glossopathy Unspecified Condition Of The Tongue
Immune System Disease	Abnormality Of The Immune System Immune System And Disorders Immune System Diseases
Aortic Aneurysm	Aortic Rupture Thoracoabdominal Aortic Aneurysm, Ruptured Ruptured Aortic Aneurysm Aortic Aneurysms Aortic Aneurysm Without Mention Of Rupture Nos Ruptured Abdominal Aortic Aneurysm Aortic Aneurysm, Ruptured Ruptured Thoracic Aortic Aneurysm
Colorectal Adenoma	Colorectal Adenomas Adenoma Of Large Intestine
Diabetic Cataract	Cataract - Diabetic
Cell Type Benign Neoplasm
Intestinal Benign Neoplasm	Intestinal Neoplasms Intestinal Tumors Intestine Growth Neoplasm Of Intestinal Tract
Tongue Carcinoma	Tongue Cancer Malignant Neoplasm Of Tongue Tongue Neoplasms Tongue Neoplasm
Colon Adenoma	Adenomatous Polyp Of Colon
Aortic Disease	Aortic Diseases Aortic Disorder Disorder Of The Aorta
Cervix Disease	Uterine Cervical Diseases Cervix Disorders Cervix Diseases
Male Reproductive System Disease	Genital Diseases, Male Disorder Of Male Reproductive System
Male Reproductive Organ Cancer	Genital Neoplasms, Male Male Genital Cancer Male Genital Neoplasm Male Reproductive System Neoplasm Malignant Neoplasm Of Male Genital Organ Malignant Neoplasm Of Male Genital Organ Or Tract Malignant Neoplasm Of Male Genital Organs Malignant Tumor Of Male Genital Organ Malignant Tumor Of Male Reproductive System Neoplasm Of Male Genital Organ Tumor Of Male Reproductive System
Gastrointestinal System Benign Neoplasm
Reproductive System Disease	Abnormality Of The Genital System Genital System Disease Reproductive System Disorder
Sensory System Disease
Uterine Anomalies	Uterine Diseases Uterine Disease Uterine Abnormality
Cervix Carcinoma	Cancer Of Cervix Carcinoma Of Cervix Carcinoma Cervix Uteri Carcinoma Of The Cervix Uteri
Female Reproductive System Disease	Genital Diseases, Female Female Reproductive System Disorder
Tongue Squamous Cell Carcinoma	Squamous Cell Carcinoma Of Tongue
Aortic Aneurysm, Familial Abdominal, 1	Abdominal Aortic Aneurysm Aortic Aneurysm, Familial Abdominal 1 Aneurysm, Abdominal Aortic AAA Aortic Aneurysm, Abdominal AAA1 Aortic Aneurysm, Familial Abdominal Aortic Aneurysm Abdominal Abdominal Aortic Aneurysms Abdominal Aortic Aneurysm Without Mention Of Perforation Or Rupture Abdomen Aneurysm Abdominal Aorta Aneurysm Aneurysm Of Abdominal Aorta Aortic Abdomen Aneurysm Aaa - [Abdominal Aortic Aneurysm] Abdominal Aneurysm Abdominal Aorta Aneurysm Rupture Abdominal Aorta Aneurysm Ruptured Abdominal Aortic Aneurysm Which Has Ruptured Ruptured Aaa Abdomen Aorta Aneurysm Ruptured Abdomen Aorta Rupture Abdomen Aortic Aneurysm Rupture Abdomen Aneurysm Rupture Abdomen Aortic Aneurysm Ruptured Abdomen Aortic Rupture Abdominal Aorta Rupture Abdominal Aortic Rupture Rupture Abdomen Aorta Aneurysm Rupture Abdominal Aortic Aneurysm Ruptured Abdomen Aneurysm Ruptured Abdomen Aorta Ruptured Abdomen Aortic Ruptured Abdominal Aneurysm Ruptured Abdominal Aorta Ruptured Abdominal Aortic Ruptured Aorta Abdominalis Aneurysm False Abdomen Aorta Aneurysm Ruptured False Abdominal Aortic Aneurysm Ruptured False Abdominal Aorta Aneurysm Ruptured False Abdomen Aortic Aneurysm Ruptured
Retinal Disease	Retinal Diseases Retinal Disorder Retinal Disorders
Cervical Cancer	Cervical Cancer, Somatic Neoplasm Of Uterine Cervix Cervix Cancer Uterine Cervical Neoplasm Cervical Neoplasm Cervix Uteri Cancer Tumor Of The Cervix Uteri CERCA Uterine Cervical Cancer Neoplasms Cervical Uterine Cervical Neoplasms Cervical Cancers Cancer, Cervical, Somatic Malignant Tumor Of Cervix Cervix Carcinoma
Respiratory System Cancer
Cardiovascular Organ Benign Neoplasm
Gastrointestinal System Cancer	Digestive System Neoplasms Gastrointestinal Neoplasms Digestive System Cancer Gastrointestinal Tract Cancer Gi Tumor Digestive System Neoplasm Digestive System Carcinoma Malignant Neoplasm Of Gastrointestinal Tract Cancer Of Digestive System
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Bladder Disease	Bladder Diseases Urinary Bladder Diseases Urinary Bladder Disease
Prostate Disease	Prostatic Diseases Prostate Diseases
Hematologic Cancer	Hematologic Neoplasm Hematologic Neoplasms Hematologic Malignancies Blood Cancer Hematologic Malignancy Hematological Tumors Hematopoietic And Lymphoid System Tumor Hematopoietic Cancer Hematopoietic Neoplasm Hematopoietic Tumors Malignant Hematopoietic Neoplasm Liquid Tumor Hematopoietic Neoplasms
Urinary System Disease	Abnormality Of The Urinary System Non-Neoplastic Urinary Tract Disease Urinary Tract Disease Urinary Tract Diseases Urinary Tract Anomaly Urologic Diseases Non-Neoplastic Urinary System Disorder Congenital Malformation Of The Urinary System
Retinal Cancer	Malignant Neoplasm Of Retina Retinal Neoplasms Malignant Retinal Neoplasm Malignant Tumor Of Retina Neoplasm Of Retina Retinal Tumor Retinal Neoplasm Cancer Of The Retina Malignant Retinal Tumour Malignant Tumour Of Retina Primary Malignant Neoplasm Of Retina
Colonic Benign Neoplasm	Colon Neoplasm Colonic Mass Colonic Tumor Neoplasm Of Colon Neoplasm Of The Colon Colonic Neoplasms Colon Cancer Colon Carcinoma Nos Colonic Cancer Metastatic Colon Cancer Nos
Gastrointestinal System Disease	Gastrointestinal Disease Gastrointestinal Diseases Alimentary System Disease Digestive System Disorder Gastroenteropathy Gastrointestinal Disorder Git Disease Digestive System Diseases Gastrointestinal Disorders Digestive System Disease Digestive System Disorders
Oral Cavity Cancer	Malignant Neoplasm Of Floor Of Mouth Oral Cavity Carcinoma Malignant Neoplasm Of Mouth
Stomach Disease	Gastropathy Stomach Diseases Gastric Disease Stomach Disorder Gastric Disorder Stomach Disorders
Respiratory System Disease	Abnormality Of The Respiratory System Respiration Disorders Respiratory Tract Diseases
Endocrine System Disease	Abnormality Of The Endocrine System Disorder Of Endocrine System Endocrine System Diseases
Endocrine Gland Cancer	Endocrine Neoplasm Malignant Neoplasm Of Endocrine Gland Endocrine Gland Neoplasms Endocrine Tumor Malignant Endocrine Tumor Malignant Tumour Of Endocrine Gland Neoplasm Of Endocrine Gland Neoplasm Of Endocrine System Neoplasm Of The Endocrine System Carcinoma Of Endocrine Gland
Large Intestine Cancer
Ocular Cancer	Eye Neoplasm Eye Carcinoma Eye Cancer Eye Neoplasms Malignant Eye Neoplasm Neoplasm Of Eye Neoplasm Of Eye Proper Ocular Tumor Carcinoma Of Eye Ocular Carcinoma Malignant Tumor Of Eye
Intestinal Disease	Intestinal Diseases
Head And Neck Cancer	Head And Neck Neoplasm Head And Neck Tumours Head/Neck Neoplasm Tumor Of Head And Neck Head And Neck Neoplasms Hnc Cancer, Head/Neck
Glucose Metabolism Disease	Glucose Metabolism Disorders Disorder Of Glucose Metabolism
Chromosome 13q14 Deletion Syndrome	Chromosome 13q Deletion Syndrome Deletion 13q14 Chromosome 13q Deletion 13q Deletion 13q Monosomy Deletion 13q Monosomy 13q Monosomy 13q14 Del(13)(Q14)
Carbohydrate Metabolic Disorder	Inborn Errors Of Carbohydrate Metabolism Disorder Of Carbohydrate Metabolism Carbohydrate Metabolism, Inborn Errors Disorder Of Carbohydrate Transport And Metabolism Inborn Carbohydrate Metabolism Disorder Inborn Carbohydrate Metabolic Disorder Carbohydrate Metabolism Disorder Carbohydrate Metabolism Disorders Disorders Of Carbohydrate Metabolism Congenital Disorders Of Carbohydrate Metabolism Inherited Disorders Of Carbohydrate Metabolism
Colonic Disease	Colonic Diseases Colon Disorder
Mastitis	Breast Inflammation Inflammatory Breast Disease Inflammatory Disease Of Breast Inflammation Of Non-Human Mammary Gland Inflammatory Disorder Of Breast Mastitis Nos Acute Mastitis Nos Acute Nonpuerperal Mastitis Nonpuerperal Mastitis Nos Subacute Mastitis Nos
Inherited Metabolic Disorder	Inborn Errors Of Metabolism Inborn Metabolic Disorder Inborn Metabolism Disorder Metabolic Hereditary Disorder Inborn Error Of Metabolism Metabolism, Inborn Errors
Lymphangioma	Lymphatic Malformation Lymphatic Malformations Benign Lymphangioma Congenital Lymphangioma Lymphangiomas
Lymphoma, Non-Hodgkin, Familial	Non-Hodgkin Lymphoma Lymphoma, Non-Hodgkin NHL Lymphoma, Non-Hodgkin, Somatic Lymphoma, Follicular, Somatic Familial Non-Hodgkin Lymphoma Lymphoma Non-Hodgkins Follicular Lymphoma, Somatic Lymphosarcoma Non-Hodgkins Lymphoma
Pancreas Disease	Abnormality Of The Pancreas Pancreatic Diseases
Central Nervous System Cancer	Central Nervous System Tumor Central Nervous System Tumors Cns Neoplasm Malignant Neoplasm Of Central Nervous System Malignant Tumor Of Cns Neoplasm Of Central Nervous System Malignant Neoplasm Of The Central Nervous System Neoplasm Of The Central Nervous System Central Nervous System Neoplasms Central Nervous System Neoplasm
Diffuse Large B-Cell Lymphoma	Dlbcl Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Large B-Cell Diffuse Lymphoma Lymphoma, Large B-Cell, Diffuse Dlbcl - [Diffuse Large B-Cell Lymphoma] Diffuse Large Beta Cell Lymphoma
Thoracic Cancer	Thoracic Tumor Thorax Cancer Thorax Neoplasm Tumor Of Thorax Thoracic Neoplasms
Malignant Exocrine Pancreas Neoplasm	Malignant Neoplasm Of The Exocrine Pancreas Malignant Tumor Of Exocrine Pancreas Malignant Tumour Of Exocrine Pancreas
Pharynx Cancer	Pharyngeal Cancer Pharyngeal Neoplasms Pharyngeal Neoplasm Pharynx Neoplasm Malignant Neoplasm Of Pharynx Pharyngeal Carcinoma
Malignant Astrocytoma	Astrocytic Tumor Astrocytoma Of Brain Astrocytoma Of Cerebrum Astroglioma Cerebral Astrocytoma Astrocytoma
Arteries, Anomalies Of	Artery Disease Arteriopathic Disease
Connective Tissue Cancer	Neoplasms, Connective Tissue Connective Tissue Neoplasm Mesenchymal Tissue Malignant Neoplasm Neoplasm Of Connective Tissues Tumour Of Connective Tissue
Central Nervous System Disease	Cns Disorder CNS Cns Diseases Central Nervous System Diseases
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Spinal Disease	Spinal Disorder Spinal Diseases
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy
Disease By Infectious Agent	Infectious Disease Infectious Diseases
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Scoliosis
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Connective Tissue Disease	Connective Tissue Diseases Connective Tissue Disorder Abnormality Of Connective Tissue Disorder Of Connective Tissue Connective Tissue Disorders
Lung Cancer Susceptibility 3	Lung Adenocarcinoma Adenocarcinoma Of Lung LNCR3 Adenocarcinoma Of Lung, Susceptibility To Bronchogenic Lung Adenocarcinoma Nonsmall Cell Adenocarcinoma Adenocarcinoma Lung Lung Adenocarcinomas Non-Small Cell Adenocarcinoma
Polycystic Kidney Disease 4 With Or Without Polycystic Liver Disease	Autosomal Recessive Polycystic Kidney Disease Arpkd Polycystic Kidney Disease, Autosomal Recessive Polycystic Kidney And Hepatic Disease 1 Pkhd1 PKD4 Polycystic Kidney Disease 4 With Or Without Hepatic Disease Polycystic Kidney Disease, Infantile, Type I Polycystic Kidney Disease, Infantile Type Polycystic Kidney, Autosomal Recessive Pkd3, Formerly Polycystic Kidney Disease 4, With Or Without Hepatic Disease Arpkd/Chf Ar-Pkd Polycystic Kidney Disease 4, With Or Without Polycystic Liver Disease Infantile Polycystic Kidney Disease Type I Pkd3 Kidney, Polycystic, Disease, Type 4, With/Without Hepatic Disease Polycystic Kidney Disease 3, Autosomal Dominant

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (20)

Cat. No.	Product Name	Purity	Rare Diseases
HY-R00319	hsa-miR-15a-5p mimic	93.82%	Unkown
HY-RI00318	hsa-miR-15a-3p inhibitor	96.31%	Unkown
HY-RI00319	hsa-miR-15a-5p inhibitor	97.35%	Unkown
HY-RI00319A	hsa-miR-15a-5p antagomir	95.30%	Unkown
HY-RI04246	rno-miR-15a-5p inhibitor	95.13%	Unkown
HY-R00318	hsa-miR-15a-3p mimic	/	Unkown
HY-R00318A	hsa-miR-15a-3p agomir	/	Unkown
HY-R00319A	hsa-miR-15a-5p agomir	/	Unkown
HY-R02692	mmu-miR-15a-3p mimic	/	Unkown
HY-R02692A	mmu-miR-15a-3p agomir	/	Unkown
HY-R04245	rno-miR-15a-3p mimic	/	Unkown
HY-R04245A	rno-miR-15a-3p agomir	/	Unkown
HY-R04246	rno-miR-15a-5p mimic	/	Unkown
HY-R04246A	rno-miR-15a-5p agomir	/	Unkown
HY-RI00318A	hsa-miR-15a-3p antagomir	/	Unkown
HY-RI02692	mmu-miR-15a-3p inhibitor	/	Unkown
HY-RI02692A	mmu-miR-15a-3p antagomir	/	Unkown
HY-RI04245	rno-miR-15a-3p inhibitor	/	Unkown
HY-RI04245A	rno-miR-15a-3p antagomir	/	Unkown
HY-RI04246A	rno-miR-15a-5p antagomir	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MIR15A	MGD	MGI:2676841