MIR204 - microRNA 204 Gene
Also Known as RDICC; MIRN204; mir-204; miRNA204
Species: Homo sapiens
About MIR204
This gene has 1 transcript (splice variant), 94 orthologues, 1 paralogue and is associated with 3 phenotypes.
Summary
MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Retinal Dystrophy And Iris Coloboma With Or Without Congenital Cataract |
|
|
| Cholangiocarcinoma |
|
|
| Pulmonary Hypertension, Primary, 1 |
|
|
| Leukemia, Acute Myeloid |
|
|
| Breast Cancer |
|
|
| Endometrial Adenocarcinoma |
|
|
| Insulinoma |
|
|
| Head And Neck Cancer |
|
|
| Oral Squamous Cell Carcinoma |
|
|
| Melanoma |
|
|
| Diabetic Cataract |
|
|
| Lung Cancer |
|
|
| Lens Disease |
|
|
| Larynx Cancer |
|
|
| Oral Cavity Cancer |
|
|
| Anterior Segment Dysgenesis 5 |
|
|
| Bile Duct Adenocarcinoma |
|
|
| Laryngeal Disease |
|
|
| Tongue Disease |
|
|
| Sensory System Disease |
|
|
| Bile Duct Cancer |
|
|
| Large Intestine Cancer |
|
|
| Stomach Disease |
|
|
| Bladder Disease |
|
|
| Male Reproductive Organ Cancer |
|
|
| Gastrointestinal System Cancer |
|
|
| Urinary System Disease |
|
|
| Endocrine Gland Cancer |
|
|
| Intestinal Disease |
|
|
| Male Reproductive System Disease |
|
|
| Retinal Disease |
|
|
| Reproductive System Disease |
|
|
| Gastrointestinal System Disease |
|
|
| Renal Cell Carcinoma, Nonpapillary |
|
|
| Heart Valve Disease |
|
|
| Uterine Anomalies |
|
|
| Female Reproductive System Disease |
|
|
| Endocrine System Disease |
|
|
| Respiratory System Cancer |
|
|
| Upper Respiratory Tract Disease |
|
|
| Hepatoblastoma |
|
|
| Thoracic Cancer |
|
|
| Colonic Disease |
|
|
| Aortic Disease |
|
|
| Connective Tissue Cancer |
|
|
| Nasopharyngeal Carcinoma |
|
|
| Tongue Squamous Cell Carcinoma |
|
|
| Nasopharyngeal Disease |
|
|
| Esophageal Disease |
|
|
| Cervix Disease |
|
|
| Biliary Tract Cancer |
|
|
| Pharynx Cancer |
|
|
| Ovarian Disease |
|
|
| Central Nervous System Cancer |
|
|
| Prostate Disease |
|
|
| Malignant Astrocytoma |
|
|
| Bone Chondrosarcoma |
|
|
| Bile Duct Disease |
|
|
| Lichen Disease |
|
|
| Respiratory System Disease |
|
|
| Pancreas Disease |
|
|
| Esophageal Cancer |
|
|
| Cataract |
|
|
| Retinal Cancer |
|
|
| Maxillary Sinus Cancer |
|
|
| Biliary Tract Disease |
|
|
| Spinal Disease |
|
|
| Megalocornea |
|
|
| Ocular Cancer |
|
|
| Bone Sarcoma |
|
|
| Arteries, Anomalies Of |
|
|
| Bone Cancer |
|
|
| Maxillary Sinus Squamous Cell Carcinoma |
|
|
| Breast Disease |
|
|
| Ovary Epithelial Cancer |
|
|
| Pulmonary Hypertension |
|
|
| Myocardial Infarction |
|
|
| Kidney Cancer |
|
|
| Mouth Disease |
|
|
| Central Nervous System Disease |
|
|
| Microphthalmia |
|
|
| Glucose Metabolism Disease |
|
|
| Carbohydrate Metabolic Disorder |
|
|
| Inherited Metabolic Disorder |
|
|
| Eye Disease |
|
|
| Lymphatic System Disease |
|
|
| Malignant Exocrine Pancreas Neoplasm |
|
|
| Colorectal Cancer |
|
|
| Immune System Disease |
|
|
| Lymphatic System Cancer |
|
|
| Cell Type Benign Neoplasm |
|
|
| Connective Tissue Disease |
|
|
| Nervous System Disease |
|
|
| In Situ Carcinoma |
|
|
| Brain Cancer |
|
|
| Hepatocellular Carcinoma |
|
|
| Bone Marrow Cancer |
|
|
| Gastric Cancer |
|
|
| Gastrointestinal Stromal Tumor |
|
|
| Aortic Valve Disease 1 |
|
|
| Hematologic Cancer |
|
|
| Cardiovascular System Disease |
|
|
| Squamous Cell Carcinoma, Head And Neck |
|
|
| Skin Disease |
|
|
| Alzheimer Disease, Familial, 1 |
|
|
| Fundus Dystrophy |
|
|
| Retinitis Pigmentosa |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | MIR204 | MGD | MGI:2676879 |
| Rattus norvegicus | MIR204 | RGD | RGD:2325551 |