GLRA4 - glycine receptor alpha 4 (pseudogene) Gene

Species: Homo sapiens

Gene Type: pseudo
Gene ID: 441509

Summary

This gene encodes a glycine receptor and member of the ligand-gated ion channel family of proteins. The encoded protein is missing the fourth transmembrane region compared to related proteins in mouse and rat, and experimental data suggests that the human protein is functionally inactive. However, there is strong evidence to support transcription of this gene. As a result, RefSeq, in collaboration with Ensembl-GENCODE, has determined that this locus is best described as a transcribed pseudogene. [provided by RefSeq, Aug 2019]

GLRA4 Protein Structure

Neur_chan_LBD

Neur_chan_LBD: Neurotransmitter-gated ion-channel ligand binding domain (47 - 255)

Neur_chan_memb

Neur_chan_memb: Neurotransmitter-gated ion-channel transmembrane region (262 - 348)

  • 0
  • 100
  • 200
  • 300
  • 417 a.a.

Related Diseases

Diseases Alias
Hyperekplexia

  • Hereditary Hyperekplexia

  • Kok Disease

  • Congenital Stiff Man Syndrome

  • Familial Startle Disease

  • Sthe

  • Stiff-Baby Syndrome

  • Hereditary Hyperexplexia

  • Startle Disease

  • Exaggerated Startle Reaction

  • Hyperexplexia Hereditary

  • Startle Disease, Familial

  • Startle Reaction, Exaggerated

  • Stiff-Man Syndrome, Congenital

  • Stiff-Person Syndrome, Congenital

  • Congenital Stiff-Man Syndrome

  • Congenital Stiff-Person Syndrome

  • Familial Hyperekplexia

  • Startle Syndrome

  • Stiff Baby Syndrome

  • Hyperekplexia, Hereditary

  • Stiff-Person Syndrome
Stiff-Person Syndrome

  • SPS

  • Stiff-Man Syndrome

  • Stiff Man Syndrome

  • Stiff Person Syndrome

  • Moersch-Woltman Syndrome

  • Sms

  • Stiff-Trunk Syndrome

  • Morsch Woltman Syndrome

  • Stiff Person Syndrome And Related Disorders

  • Stiff Person Spectrum Disorder

  • Classic Stiff Person Syndrome

  • Classic Sps

  • Focal Stiff Limb Syndrome

  • Focal Stiff-Person Syndrome

  • Stiff Leg Syndrome

  • Progressive Encephalomyelitis With Rigidity
Glycine Encephalopathy

  • Non-Ketotic Hyperglycinemia

  • Nonketotic Hyperglycinemia

  • NKH

  • GCE

  • Hyperglycinemia, Nonketotic

  • Hyperglycinemia Nonketotic

  • Infantile Glycine Encephalopathy

  • Encephalopathy, Glycine

  • Glycine Synthase Deficiency

  • Nka

  • Neonatal Glycine Encephalopathy

  • Classic Glycine Encephalopathy

  • Neonatal Nkh

  • Neonatal Non-Ketotic Hyperglycinemia

  • Infantile Nkh

  • Infantile Non-Ketotic Hyperglycinemia

  • Non-Ketotic Hyperglycinaemia

  • Glycine Cleavage Deficiency

  • Nonketotic Hyperglycinaemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05389 GFRA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05492 GLRA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05493 GLRA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05494 GLRA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22528 Glra1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29048 Glra1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GLRA4 VGNC VGNC:29414
Mus musculus GLRA4 MGD MGI:95750
Macaca mulatta GLRA4 VGNC VGNC:73044
Felis catus GLRA4 VGNC VGNC:62591
Canis familiaris GLRA4 VGNC VGNC:41271
Rattus norvegicus GLRA4 RGD RGD:1564103
Others GLRA4 NCBI