Tdp2 - tyrosyl-DNA phosphodiesterase 2 Gene

Rattus norvegicus

Also known as Ttrap

Gene ID: 498749 | Gene type: protein coding

About Tdp2

Summary

Predicted to enable metal ion binding activity; phosphoric diester hydrolase activity; and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair and neuron development. Predicted to be located in aggresome and nuclear body. Predicted to be active in PML body and cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 23. Orthologous to human TDP2 (tyrosyl-DNA phosphodiesterase 2). [provided by Alliance of Genome Resources, Apr 2022]

Tdp2 Products(1)

mRNA	Protein	Name
NM_001034947.1	NP_001030119.1	tyrosyl-DNA phosphodiesterase 2

Protein Preferred Names

Protein Names

tyrosyl-DNA phosphodiesterase 2

5'-Tyr-DNA phosphodiesterase	5'-tyrosyl-DNA phosphodiesterase
TRAF and TNF receptor-associated protein	Traf and Tnf receptor associated protein
tyr-DNA phosphodiesterase 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-162753	ZW-1226	Inhibitor	98.13%	Unkown
HY-RS14333	TDP2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tdp2	NCBI	NCBI:51567

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