Edaradd - EDAR-associated death domain Gene

Also Known as RGD1564010

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 498769

Summary

Involved in positive regulation of NIK/NF-kappaB signaling. Used to study hypohidrotic ectodermal dysplasia and otitis media. Human ortholog(s) of this gene implicated in ectodermal dysplasia 11A and ectodermal dysplasia 11B. Orthologous to human EDARADD (EDAR associated death domain). [provided by Alliance of Genome Resources, Apr 2022]

Edaradd Products (1)

mRNA Protein Name
XM_574055.8 XP_574055.4 ectodysplasin-A receptor-associated adapter protein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of non-canonical NF-kappaB signal transduction IMP
IMP: Inferred from mutant phenotype
22013926 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ectodysplasin-A receptor-associated adapter protein

  • EDAR (ectodysplasin-A receptor)-associated death domain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04154 EDARADD Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Edaradd NCBI NCBI:128178