Cers3 - ceramide synthase 3 Gene

Predicted to enable sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process and cornification. Predicted to act upstream of or within sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane and nucleus. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 9. Orthologous to human CERS3 (ceramide synthase 3). [provided by Alliance of Genome Resources, Apr 2022]