2. Gene
  3. Msh3 - mutS homolog 3 Gene

Msh3 - mutS homolog 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 499505 | Gene type: protein coding

About Msh3

Summary

Predicted to enable ATP-dependent activity, acting on DNA; DNA binding activity; and enzyme binding activity. Predicted to contribute to dinucleotide repeat insertion binding activity; single guanine insertion binding activity; and single-stranded DNA binding activity. Involved in spermatogenesis. Predicted to be located in nucleus. Predicted to be part of MutSbeta complex. Human ortholog(s) of this gene implicated in colorectal carcinoma; endometrial cancer; endometrial carcinoma; familial adenomatous polyposis 4; and lung non-small cell carcinoma. Orthologous to human MSH3 (mutS homolog 3). [provided by Alliance of Genome Resources, Apr 2022]

Msh3 Products(1)

mRNA Protein Name
NM_001191957.1 NP_001178886.1 DNA mismatch repair protein Msh3
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
10644444 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA mismatch repair protein Msh3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08710 MSH3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Msh3 NCBI NCBI:4437