2. Gene
  3. Ubr1 - ubiquitin protein ligase E3 component n-recognin 1 Gene

Ubr1 - ubiquitin protein ligase E3 component n-recognin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1562326

Gene ID: 499877 | Gene type: protein coding

About Ubr1

Summary

Predicted to enable leucine binding activity and ubiquitin-protein transferase activity. Predicted to be involved in cellular response to leucine and negative regulation of TOR signaling. Predicted to act upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be part of Proteasome complex and ubiquitin Ligase complex. Human ortholog(s) of this gene implicated in Johanson-Blizzard syndrome. Orthologous to human UBR1 (ubiquitin protein Ligase E3 component n-recognin 1). [provided by Alliance of Genome Resources, Apr 2022]

Ubr1 Products(1)

mRNA Protein Name
NM_001178072.1 NP_001171543.1 E3 ubiquitin-protein ligase UBR1
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase UBR1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15386 UBR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-180976 Arg-PEG1-Tαsyn Degrader / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ubr1 NCBI NCBI:197131