Sybu - syntabulin Gene

Also Known as Ocsyn; Golsyn; RGD1564335

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 500865

Summary

Enables microtubule binding activity. Involved in several processes, including axonal transport; positive regulation of Insulin secretion involved in cellular response to glucose stimulus; and regulation of synaptic activity. Acts upstream of or within regulation of Insulin secretion involved in cellular response to glucose stimulus. Located in dense body; microtubule; and vesicle. Orthologous to human SYBU (syntabulin). [provided by Alliance of Genome Resources, Apr 2022]

Sybu Products (13)

mRNA Protein Name
XM_039080175.1 XP_038936103.1 syntabulin isoform X3
XM_039080176.1 XP_038936104.1 syntabulin isoform X4
XM_006241617.3 XP_006241679.1 syntabulin isoform X5
XM_006241616.3 XP_006241678.1 syntabulin isoform X3
XM_039080173.1 XP_038936101.1 syntabulin isoform X2
XM_039080172.1 XP_038936100.1 syntabulin isoform X1
XM_039080177.1 XP_038936105.1 syntabulin isoform X4
XM_039080174.1 XP_038936102.1 syntabulin isoform X3
XM_039080181.1 XP_038936109.1 syntabulin isoform X8
XM_039080183.1 XP_038936111.1 syntabulin isoform X8
XM_039080182.1 XP_038936110.1 syntabulin isoform X8
XM_039080180.1 XP_038936108.1 syntabulin isoform X7
XM_039080178.1 XP_038936106.1 syntabulin isoform X6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
22975310 RGD
Biological Process GO Annotation Evidence References Source
involved in anterograde neuronal dense core vesicle transport IMP
IMP: Inferred from mutant phenotype
17611281 RGD
involved in axonal transport of mitochondrion IMP
IMP: Inferred from mutant phenotype
19828815 RGD
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
22975310 RGD
acts upstream of or within regulation of insulin secretion involved in cellular response to glucose stimulus IDA
IDA: Inferred from direct assay
22975310 RGD
involved in regulation of synaptic activity IMP
IMP: Inferred from mutant phenotype
19828815 RGD
involved in synapse maturation IMP
IMP: Inferred from mutant phenotype
19828815 RGD
Cellular Component GO Annotation Evidence References Source
located in dense body IDA
IDA: Inferred from direct assay
22975310 RGD
located in microtubule IDA
IDA: Inferred from direct assay
22975310 RGD
located in vesicle IDA
IDA: Inferred from direct assay
22975310 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

syntabulin

  • Golgi-localized protein

  • syntabulin (syntaxin-interacting)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14067 SYBU Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sybu NCBI NCBI:55638