TAS2R1 - taste 2 receptor member 1 Gene

Also Known as T2R1; TRB7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 50834

About TAS2R1

Cytogenetic location: 5p15.31-p15.2 Genomic coordinates (GRCh38): 5:9,627,347-9,903,876 (from NCBI)

This gene has 3 transcripts (splice variants), 162 orthologues and 23 paralogues.

Summary

This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by Taste Receptor cells of the tongue and palate epithelia. This intronless Taste Receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter Taste Receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil. [provided by RefSeq, Jul 2008]

TAS2R1 Products (2)

mRNA Protein Name
NM_001386348.1 NP_001373277.1 taste receptor type 2 member 1 isoform 2
NM_019599.3 NP_062545.1 taste receptor type 2 member 1 isoform 1

TAS2R1 Protein Structure

TAS2R

TAS2R: Taste receptor protein (TAS2R) (1 - 296)

  • 0
  • 100
  • 200
  • 299 a.a.
Protein Preferred Names Protein Names

taste receptor type 2 member 1

  • taste receptor, family B, member 7

Related Diseases

Diseases Alias
Cri-Du-Chat Syndrome
  • 5p Deletion Syndrome

  • 5p Partial Monosomy Syndrome

  • Monosomy 5p

  • Cat Cry Syndrome

  • Chromosome 5p Deletion Syndrome

  • Cri Du Chat Syndrome

  • 5p- Syndrome

  • 5p Minus Syndrome

  • Chromosome 5p- Syndrome

  • Chromosome 5 Short Arm Deletion Syndrome

  • Chromosome 5p Deletion

  • Deletion 5p

  • Cri Du Chat

  • 5p Partial Deletion Syndrome

  • Partial Deletion Of Short Arm Of Chromosome 5 Syndrome

Autism
  • Autistic Disorder

  • Autism Susceptibility 1

  • Childhood Autism

  • Autistic Disorder Of Childhood Onset

  • Infantile Autism

  • Kanner'S Syndrome

  • Autistic

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TAS2R1 RGD RGD:620733
Canis familiaris TAS2R1 VGNC VGNC:47114
Felis catus TAS2R1 VGNC VGNC:65959
Macaca mulatta TAS2R1 VGNC VGNC:110429
Mus musculus TAS2R1 MGD MGI:2681253
Bos taurus TAS2R1 VGNC VGNC:35609
Others TAS2R1 NCBI