TAS2R1 - taste 2 receptor member 1 Gene
Also Known as T2R1; TRB7
Species: Homo sapiens
About TAS2R1
This gene has 3 transcripts (splice variants), 162 orthologues and 23 paralogues.
Summary
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by Taste Receptor cells of the tongue and palate epithelia. This intronless Taste Receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter Taste Receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil. [provided by RefSeq, Jul 2008]
TAS2R1 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001386348.1 | NP_001373277.1 | taste receptor type 2 member 1 isoform 2 |
| NM_019599.3 | NP_062545.1 | taste receptor type 2 member 1 isoform 1 |
TAS2R1 Protein Structure
TAS2R: Taste receptor protein (TAS2R) (1 - 296)
- 0
- 100
- 200
- 299 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
taste receptor type 2 member 1 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Cri-Du-Chat Syndrome |
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| Autism |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | TAS2R1 | RGD | RGD:620733 |
| Canis familiaris | TAS2R1 | VGNC | VGNC:47114 |
| Felis catus | TAS2R1 | VGNC | VGNC:65959 |
| Macaca mulatta | TAS2R1 | VGNC | VGNC:110429 |
| Mus musculus | TAS2R1 | MGD | MGI:2681253 |
| Bos taurus | TAS2R1 | VGNC | VGNC:35609 |
| Others | TAS2R1 | NCBI |