SIDT2 - SID1 transmembrane family member 2 Gene

Also Known as CGI-40

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51092

About SIDT2

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:117,178,743-117,197,442 (from NCBI)

This gene has 20 transcripts (splice variants), 202 orthologues and 1 paralogue. Ubiquitous expression in stomach (RPKM 22.3), prostate (RPKM 21.9) and 25 other tissues.

Summary

Predicted to enable several functions, including AP-1 adaptor complex binding activity; AP-2 adaptor complex binding activity; and RNA transmembrane transporter activity. Involved in RNA transport. Located in lysosomal membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SIDT2 Products (1)

mRNA Protein Name
NM_001040455.2 NP_001035545.1 SID1 transmembrane family member 2 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in RNA transport IDA
IDA: Inferred from direct assay
28277980 GOA
Cellular Component GO Annotation Evidence References Source
located in lysosomal membrane IDA
IDA: Inferred from direct assay
17897319 GOA
located in lysosome IDA
IDA: Inferred from direct assay
28277980 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
28277980 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SIDT2 Protein Structure

SID-1_RNA_chan

SID-1_RNA_chan: dsRNA-gated channel SID-1 (170 - 832)

  • 0
  • 200
  • 400
  • 600
  • 832 a.a.
Protein Preferred Names Protein Names

SID1 transmembrane family member 2

Related Diseases

Diseases Alias
Gastrointestinal Adenoma

  • Gi Adenoma

  • Digestive System Adenoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12895 SIDT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SIDT2 VGNC VGNC:34615
Felis catus SIDT2 VGNC VGNC:65139
Mus musculus SIDT2 MGD MGI:2446134
Canis familiaris SIDT2 VGNC VGNC:46166
Rattus norvegicus SIDT2 RGD RGD:1308311
Macaca mulatta SIDT2 VGNC VGNC:77300
Others SIDT2 NCBI