PHF11 - PHD finger protein 11 Gene

Homo sapiens

Also known as APY; BCAP; IGEL; IGER; IGHER; NYREN34; NY-REN-34

Gene ID: 51131 | Gene type: protein coding

About PHF11

Cytogenetic location: 13q14.2 Genomic coordinates (GRCh38): 13:49,495,953-49,528,992 (from NCBI)

This gene has 18 transcripts (splice variants), 133 orthologues and 3 paralogues. Ubiquitous expression in lymph node (RPKM 13.0), spleen (RPKM 12.7) and 25 other tissues.

Summary

This gene encodes a protein containing a PHD (plant homeodomain) type zinc finger. This gene has been identified in some studies as a candidate gene for asthma. Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

PHF11 Products(2)

mRNA	Protein	Name
NM_001040443.3	NP_001035533.1	PHD finger protein 11 isoform a
NM_001040444.2	NP_001035534.1	PHD finger protein 11 isoform b

PHF11 Protein Structure

zf-HC5HC2H

0
100
200
300
331 a.a.

Protein Preferred Names

Protein Names

PHD finger protein 11

BRCA1 C-terminus-associated protein

Related Diseases

Diseases

Alias

Asthma

Chronic Obstructive Asthma	Asthma, Diminished Response To Antileukotriene Treatment In
Bronchial Hyperreactivity	Asthma, Susceptibility To
Asthma, Bronchial	Asthma, Protection Against
Asthma, Nocturnal, Susceptibility To	Nocturnal Asthma
Asthma-Related Traits	Asthma-Related Traits, Susceptibility To
Asthma, Nocturnal	Chronic Obstructive Asthma With Acute Exacerbation
Chronic Obstructive Asthma With Status Asthmaticus	Exercise Induced Asthma
Exercise-Induced Asthma	Bronchial Asthma
Asthma, Exercise-Induced	Idiosyncratic Asthma
Unspecified Asthma With Acute Exacerbation	Asthma, Unspecified, With Stated Status Asthmaticus
Status Asthmaticus Nos	Acute Severe Asthma
Acute Severe Bronchial Asthma	Status Asthma
Status Post Asthmaticus

Near-Fatal Asthma

Ige Responsiveness, Atopic

ATOPY	Atopy, Susceptibility To
Ige, Elevated Level Of	IGER
Immunoglobulin E, Basic Level Of, In Serum	Ige, Level Of
Igel	Ige Response Underlying Allergic Asthma And Rhinitis
Atopic Hypersensitivity	Immediate Hypersensitivity

Dermatitis, Atopic

Atopic Dermatitis	Atopic Eczema
Dermatitis, Atopic, Susceptibility To, 1	Atod
Eczema, Atopic	Dermatitis, Atopic 1
Allergic Dermatitis	Atopic Neurodermatitis
Besnier'S Prurigo	Dermatitis, Atopic, 1
Dermatitis Atopic	Eczema
Besnier Prurigo

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10415	PHF11 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	PHF11	VGNC	VGNC:104698
Bos taurus	PHF11	VGNC	VGNC:106864
Canis familiaris	PHF11	VGNC	VGNC:44481
Rattus norvegicus	PHF11	RGD	RGD:1310853
Macaca mulatta	PHF11	VGNC	VGNC:75814

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