LSR - lipolysis stimulated lipoprotein receptor Gene

Also Known as ILDR3; LISCH7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51599

About LSR

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,249,002-35,267,964 (from NCBI)

This gene has 14 transcripts (splice variants), 189 orthologues and 2 paralogues. Broad expression in stomach (RPKM 52.0), colon (RPKM 51.5) and 22 other tissues.

Summary

Predicted to be involved in several processes, including establishment of skin barrier; protein localization to tricellular tight junction; and tricellular tight junction assembly. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

LSR Products (6)

mRNA Protein Name
NM_001260489.2 NP_001247418.2 lipolysis-stimulated lipoprotein receptor isoform 4 precursor
NM_001260490.2 NP_001247419.2 lipolysis-stimulated lipoprotein receptor isoform 5 precursor
NM_001385215.1 NP_001372144.1 lipolysis-stimulated lipoprotein receptor isoform 6 precursor
NM_015925.7 NP_057009.4 lipolysis-stimulated lipoprotein receptor isoform 1 precursor
NM_205834.4 NP_991403.2 lipolysis-stimulated lipoprotein receptor isoform 2 precursor
NM_205835.4 NP_991404.2 lipolysis-stimulated lipoprotein receptor isoform 3 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in tight junction IDA
IDA: Inferred from direct assay
23239027 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LSR Protein Structure

LSR

LSR: Lipolysis stimulated receptor (LSR) (259 - 306)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600
  • 649 a.a.
Protein Preferred Names Protein Names

lipolysis-stimulated lipoprotein receptor

  • LISCH protein

Related Diseases

Diseases Alias
Familial Intrahepatic Cholestasis
Deafness, Autosomal Recessive 42

  • DFNB42

  • Autosomal Recessive Nonsyndromic Deafness 42

  • Autosomal Recessive Deafness 42

  • Deafness, Autosomal Recessive, 42

  • Congenital Neurosensory Deafness Autosomal Recessive 42

  • Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 42

  • Non-Syndromic Sensorineural Deafness Autosomal Recessive Type 42

  • Deafness, Autosomal Recessive, Type 42
Deafness, Autosomal Recessive 49

  • DFNB49

  • Autosomal Recessive Nonsyndromic Deafness 49

  • Autosomal Recessive Deafness 49

  • Deafness, Autosomal Recessive, 49

  • Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 49

  • Non-Syndromic Sensorineural Deafness Autosomal Recessive Type 49

  • Deafness, Autosomal Recessive, Type 49
Intrahepatic Cholestasis

  • Cholestasis, Intrahepatic

  • Neonatal Intrahepatic Cholestasis

  • Cholestasis Intrahepatic

  • Cholestasis Of Pregnancy
Retinitis Pigmentosa 48

  • RP48

  • Retinitis Pigmentosa, Type 48
Clostridium Difficile Colitis

  • Pseudomembranous Colitis

  • Colitis Pseudomembranous

  • Enterocolitis, Pseudomembranous

  • Pseudomembranous Enterocolitis

  • Clostridium Difficile Infection
Pontocerebellar Hypoplasia, Type 16

  • PCH16

  • Pontocerebellar Hypoplasia Type 16

  • Pontocerebellar Hypoplasia 16

  • Doid:0112333
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07865 LSR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21285 Lsr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27804 Lsr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus LSR VGNC VGNC:31064
Mus musculus LSR MGD MGI:1927471
Canis familiaris LSR VGNC VGNC:42850
Rattus norvegicus LSR RGD RGD:69236
Macaca mulatta LSR VGNC VGNC:74396
Felis catus LSR VGNC VGNC:63326
Others LSR NCBI