LSR - lipolysis stimulated lipoprotein receptor Gene

Homo sapiens

Also known as ILDR3; LISCH7

Gene ID: 51599 | Gene type: protein coding

About LSR

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,249,002-35,267,964 (from NCBI)

This gene has 14 transcripts (splice variants), 189 orthologues and 2 paralogues. Broad expression in stomach (RPKM 52.0), colon (RPKM 51.5) and 22 other tissues.

Summary

Predicted to be involved in several processes, including establishment of skin barrier; protein localization to tricellular tight junction; and tricellular tight junction assembly. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

LSR Products(6)

mRNA	Protein	Name
NM_001260489.2	NP_001247418.2	lipolysis-stimulated lipoprotein receptor isoform 4 precursor
NM_001260490.2	NP_001247419.2	lipolysis-stimulated lipoprotein receptor isoform 5 precursor
NM_001385215.1	NP_001372144.1	lipolysis-stimulated lipoprotein receptor isoform 6 precursor
NM_015925.7	NP_057009.4	lipolysis-stimulated lipoprotein receptor isoform 1 precursor
NM_205834.4	NP_991403.2	lipolysis-stimulated lipoprotein receptor isoform 2 precursor
NM_205835.4	NP_991404.2	lipolysis-stimulated lipoprotein receptor isoform 3 precursor

LSR Protein Structure

LSR

0
100
200
300
400
500
600
649 a.a.

Protein Preferred Names

Protein Names

lipolysis-stimulated lipoprotein receptor

LISCH protein

Related Diseases

Diseases

Alias

Familial Intrahepatic Cholestasis

Deafness, Autosomal Recessive 42

DFNB42	Autosomal Recessive Nonsyndromic Deafness 42
Autosomal Recessive Deafness 42	Deafness, Autosomal Recessive, 42
Congenital Neurosensory Deafness Autosomal Recessive 42	Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 42
Non-Syndromic Sensorineural Deafness Autosomal Recessive Type 42	Deafness, Autosomal Recessive, Type 42

Deafness, Autosomal Recessive 49

DFNB49	Autosomal Recessive Nonsyndromic Deafness 49
Autosomal Recessive Deafness 49	Deafness, Autosomal Recessive, 49
Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 49	Non-Syndromic Sensorineural Deafness Autosomal Recessive Type 49
Deafness, Autosomal Recessive, Type 49

Intrahepatic Cholestasis

Cholestasis, Intrahepatic	Neonatal Intrahepatic Cholestasis
Cholestasis Intrahepatic	Cholestasis Of Pregnancy

Retinitis Pigmentosa 48

RP48	Retinitis Pigmentosa, Type 48

Clostridium Difficile Colitis

Pseudomembranous Colitis	Colitis Pseudomembranous
Enterocolitis, Pseudomembranous	Pseudomembranous Enterocolitis
Clostridium Difficile Infection

Pontocerebellar Hypoplasia, Type 16

PCH16	Pontocerebellar Hypoplasia Type 16
Pontocerebellar Hypoplasia 16	Doid:0112333

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07865	LSR Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	LSR	VGNC	VGNC:31064
Mus musculus	LSR	MGD	MGI:1927471
Canis familiaris	LSR	VGNC	VGNC:42850
Rattus norvegicus	LSR	RGD	RGD:69236
Macaca mulatta	LSR	VGNC	VGNC:74396
Felis catus	LSR	VGNC	VGNC:63326