Nus1 - NUS1 dehydrodolichyl diphosphate synthase subunit Gene

Also Known as D10Ertd438e; 1600027K07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 52014

Summary

Enables prenyltransferase activity. Acts upstream of or within Cholesterol homeostasis; protein mannosylation; and regulation of intracellular Cholesterol transport. Located in membrane. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 55 and congenital disorder of glycosylation Iaa. Orthologous to human NUS1 (NUS1 dehydrodolichyl diphosphate synthase subunit). [provided by Alliance of Genome Resources, Apr 2022]

Nus1 Products (1)

mRNA Protein Name
NM_030250.2 NP_084526.1 dehydrodolichyl diphosphate synthase complex subunit Nus1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables prenyltransferase activity IMP
IMP: Inferred from mutant phenotype
25066056 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cholesterol homeostasis IMP
IMP: Inferred from mutant phenotype
25066056 MGI
acts upstream of or within protein mannosylation IMP
IMP: Inferred from mutant phenotype
25066056 MGI
acts upstream of or within regulation of intracellular cholesterol transport IMP
IMP: Inferred from mutant phenotype
19723497 MGI
acts upstream of or within sterol homeostasis IMP
IMP: Inferred from mutant phenotype
19723497 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IMP
IMP: Inferred from mutant phenotype
25066056 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dehydrodolichyl diphosphate synthase complex subunit Nus1

  • Nogo-B receptor

  • dehydrodolichyl diphosphate syntase complex subunit Nus1

  • di-trans,poly-cis-decaprenylcistransferase

  • ngBR

  • nuclear undecaprenyl pyrophosphate synthase 1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09703 NUS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nus1 NCBI NCBI:116150