Mfhas1 - malignant fibrous histiocytoma amplified sequence 1 Gene

Also Known as D8Ertd91e; 2310066G09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 52065

Summary

Predicted to enable GTP binding activity; protein Phosphatase 2A binding activity; and ubiquitin protein Ligase binding activity. Involved in inflammatory response; innate immune response; and regulation of Toll-like Receptor 2 signaling pathway. Predicted to be located in cytoplasm. Is expressed in central nervous system; dorsal root ganglion; neural retina; and vibrissa. Orthologous to human MFHAS1 (multifunctional ROCO family signaling regulator 1). [provided by Alliance of Genome Resources, Apr 2022]

Mfhas1 Products (2)

mRNA Protein Name
NM_001081279.2 NP_001074748.1 malignant fibrous histiocytoma-amplified sequence 1 homolog isoform 1
NM_001364259.1 NP_001351188.1 malignant fibrous histiocytoma-amplified sequence 1 homolog isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in defense response IMP
IMP: Inferred from mutant phenotype
20616063 MGI
involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
26599367 MGI
involved in innate immune response IMP
IMP: Inferred from mutant phenotype
26599367 MGI
involved in negative regulation of toll-like receptor 2 signaling pathway IMP
IMP: Inferred from mutant phenotype
26599367 MGI
involved in positive regulation of toll-like receptor 2 signaling pathway IMP
IMP: Inferred from mutant phenotype
26599367 MGI
involved in regulation of toll-like receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
20616063 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

malignant fibrous histiocytoma-amplified sequence 1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08382 MFHAS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mfhas1 NCBI NCBI:9258