2. Gene
  3. RORB - RAR related orphan receptor B Gene

RORB - RAR related orphan receptor B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Bos taurus
Gene ID: 528382 | Gene type: protein coding

About RORB

Primary_assembly 8: 50,559,389-50,763,952 forward strand.ARS-UCD1.2:CM008175.2

This gene has 2 transcripts (splice variants), 398 orthologues and 18 paralogues.

Summary

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm. [provided by RefSeq, Feb 2014]

RORB Products(1)

mRNA Protein Name
NM_001192658.1 NP_001179587.1 nuclear receptor ROR-beta

RORB Protein Structure

NR_DBD_ROR

NR_DBD_ROR: cd06968 (27 - 121)

NR_LBD_ROR_like

NR_LBD_ROR_like: cd06939 (234 - 474)

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  • 484 a.a.
Protein Preferred Names Protein Names

nuclear receptor ROR-beta

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12129 RORB Human Pre-designed siRNA Set A / Unkown
HY-RS12130 Rorb Mouse Pre-designed siRNA Set A / Unkown
HY-RS12131 Rorb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens RORB NCBI NCBI:6096