GDPD2 - glycerophosphodiester phosphodiesterase domain containing 2 Gene

Also Known as GDE3; OBDPF

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54857

About GDPD2

Cytogenetic location: Xq13.1 Genomic coordinates (GRCh38): X:70,423,314-70,433,381 (from NCBI)

This gene has 5 transcripts (splice variants), 207 orthologues and 5 paralogues. Biased expression in spleen (RPKM 25.5), skin (RPKM 21.4) and 4 other tissues.

Summary

This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. This protein may have a role in osteoblast differentiation and growth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

GDPD2 Products (4)

mRNA Protein Name
NM_001171191.2 NP_001164662.1 glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 3
NM_001171192.2 NP_001164663.1 glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 1
NM_001171193.2 NP_001164664.1 glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 3
NM_017711.4 NP_060181.2 glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform 2

GDPD2 Protein Structure

GDPD

GDPD: Glycerophosphoryl diester phosphodiesterase family (229 - 359)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 539 a.a.
Protein Preferred Names Protein Names

glycerophosphoinositol inositolphosphodiesterase GDPD2

  • glycerophosphodiester phosphodiesterase 3

Related Diseases

Diseases Alias
Junctional Epidermolysis Bullosa Non-Herlitz Type

  • Junctional Epidermolysis Bullosa, Non-Herlitz Type

  • Gabeb

  • Generalized Atrophic Benign Epidermolysis Bullosa

  • Generalized Junctional Epidermolysis Bullosa, Non-Herlitz Type

  • Jeb-Nh Gen

  • Jen-Nh

  • Junctional Epidermolysis Bullosa Generalisata Mitis

  • Junctional Epidermolysis Bullosa, Disentis Type

  • Epidermolysis Bullosa, Junctional, Non-Herlitz Type
Lynch Syndrome I

  • Lynch Syndrome 1

  • Colorectal Cancer, Hereditary Nonpolyposis, Type 1

  • HNPCC1

  • Fcc1

  • Lynch Syndrome Ii

  • Colon Cancer, Familial Nonpolyposis, Type 1

  • Coca1

  • Familial Nonpolyposis Colon Cancer Type 1

  • Hereditary Nonpolyposis Colorectal Cancer Type 1

  • Hereditary Non-Polyposis Colorectal Cancer 1

  • Hereditary Non-Polyposis Colorectal Cancer 3

  • Hnpcc3

  • Lynch Cancer Family Syndrome

  • Lynch Syndrome

  • Lynch Syndrome Type I

  • Lynch Syndrome Type Ii

  • Cancer, Colorectal, Nonpolyposis, Hereditary, Type 1

  • Hereditary Nonpolyposis Colorectal Cancer

  • Colorectal Cancer, Hereditary Nonpolyposis, Type 3

  • Hereditary Non-Polyposis Colon Cancer Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05363 GDPD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GDPD2 MGD MGI:1918834
Felis catus GDPD2 VGNC VGNC:62508
Bos taurus GDPD2 VGNC VGNC:29311
Rattus norvegicus GDPD2 RGD RGD:1560780
Canis familiaris GDPD2 VGNC VGNC:41167
Macaca mulatta GDPD2 VGNC VGNC:72787
Others GDPD2 NCBI