RETSAT - retinol saturase Gene
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 54884
About RETSAT
Cytogenetic location: 2p11.2
Genomic coordinates (GRCh38): 2:85,341,955-85,354,528 (from NCBI)
This gene has 7 transcripts (splice variants), 219 orthologues and 2 paralogues. Broad expression in fat (RPKM 182.7), duodenum (RPKM 78.0) and 17 other tissues.
Summary
Predicted to enable all-trans-retinol 13,14-reductase activity. Predicted to be involved in retinol metabolic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]
RETSAT Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_017750.4 | NP_060220.3 | all-trans-retinol 13,14-reductase precursor |
RETSAT Protein Structure
NAD_binding_8
NAD_binding_8: NAD(P)-binding Rossmann-like domain (72 - 124)
- 0
- 100
- 200
- 300
- 400
- 500
- 610 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
all-trans-retinol 13,14-reductase |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Macular Degeneration, Age-Related, 10 |
|
|
| Gastric Cardia Carcinoma |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS11860 | RETSAT Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | RETSAT | VGNC | VGNC:97818 |
| Mus musculus | RETSAT | MGD | MGI:1914692 |
| Canis familiaris | RETSAT | VGNC | VGNC:45486 |
| Rattus norvegicus | RETSAT | RGD | RGD:628802 |
| Bos taurus | RETSAT | VGNC | VGNC:33881 |
| Felis catus | RETSAT | VGNC | VGNC:81170 |
| Others | RETSAT | NCBI |
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