KCNK12 - potassium two pore domain channel subfamily K member 12 Gene

Also Known as THIK2; THIK-2; K2p12.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56660

About KCNK12

Cytogenetic location: 2p16.3 Genomic coordinates (GRCh38): 2:47,509,290-47,570,985 (from NCBI)

This gene has 2 transcripts (splice variants), 213 orthologues and 14 paralogues. Biased expression in brain (RPKM 1.7), placenta (RPKM 0.4) and 8 other tissues.

Summary

This gene encodes one of the members of the superfamily of Potassium Channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require Other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]

KCNK12 Products (1)

mRNA Protein Name
NM_022055.2 NP_071338.1 potassium channel subfamily K member 12

KCNK12 Protein Structure

Ion_trans_2

Ion_trans_2: Ion channel (112 - 168)

Ion_trans_2

Ion_trans_2: Ion channel (224 - 302)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 430 a.a.
Protein Preferred Names Protein Names

potassium channel subfamily K member 12

  • potassium channel, subfamily K, member 12

Related Diseases

Diseases Alias
Developmental And Epileptic Encephalopathy 52

  • DEE52

  • Epileptic Encephalopathy, Early Infantile, 52

  • Eiee52

  • Developmental And Epileptic Encephalopathy, 52

  • Early Infantile Epileptic Encephalopathy 52
Skin Angiosarcoma

  • Angiosarcoma Of Skin

  • Hemangiosarcoma Of The Skin

  • Haemangiosarcoma Of Skin

  • Lymphangiosarcoma Of Skin

  • Cutaneous Angiosarcoma

  • Malignant Haemangioendothelioma Of Skin
Brugada Syndrome 5

  • BRGDA5

  • Cardiac Conduction Defect, Nonspecific

  • Brugada Syndrome, Type 5
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07154 KCNK12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris KCNK12 VGNC VGNC:42271
Macaca mulatta KCNK12 VGNC VGNC:106176
Bos taurus KCNK12 VGNC VGNC:30467
Rattus norvegicus KCNK12 RGD RGD:68940
Mus musculus KCNK12 MGD MGI:2684043
Others KCNK12 NCBI