TXNDC16 - thioredoxin domain containing 16 Gene

Also Known as ERp90; KIAA1344

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57544

About TXNDC16

Cytogenetic location: 14q22.1 Genomic coordinates (GRCh38): 14:52,430,596-52,552,505 (from NCBI)

This gene has 4 transcripts (splice variants) and 199 orthologues. Ubiquitous expression in prostate (RPKM 12.7), brain (RPKM 6.3) and 25 other tissues.

Summary

Located in endoplasmic reticulum lumen. [provided by Alliance of Genome Resources, Apr 2022]

TXNDC16 Products (2)

mRNA Protein Name
NM_001160047.2 NP_001153519.1 thioredoxin domain-containing protein 16 isoform 2 precursor
NM_020784.3 NP_065835.2 thioredoxin domain-containing protein 16 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21359175 GOA
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
21359175 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TXNDC16 Protein Structure

Thioredoxin

Thioredoxin: Thioredoxin (394 - 493)

Thioredoxin_6

Thioredoxin_6: Thioredoxin-like domain (533 - 722)

  • 0
  • 200
  • 400
  • 600
  • 825 a.a.
Protein Preferred Names Protein Names

thioredoxin domain-containing protein 16

Related Diseases

Diseases Alias
Post-Vaccinal Encephalitis

  • Encephalitis Following Immunization Procedures

  • Postvaccinal Encephalomyelitis

  • Encephalomyelitis, Acute Disseminated
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15292 TXNDC16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TXNDC16 RGD RGD:1306755
Bos taurus TXNDC16 VGNC VGNC:36537
Mus musculus TXNDC16 MGD MGI:1917811
Macaca mulatta TXNDC16 VGNC VGNC:79214
Felis catus TXNDC16 VGNC VGNC:66727
Canis familiaris TXNDC16 VGNC VGNC:48013
Others TXNDC16 NCBI