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No matches for "

63948

" within the MedChemExpress (MCE) catalog. Here are the results you might be looking for.

By Targets:	Drug Derivative (1) Histamine Receptor (1) IPK Superfamily (1) MicroRNA (20) PPAR (1)
By Research Areas:	Cancer (20) Endocrinology (1) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (1)
Oligonucleotides:	miRNA mimics (5) miRNA agomirs (5) miRNA antagomirs (5) MicroRNAs (20) miRNA inhibitors (5)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-19048

CP-66948	Histamine Receptor	Endocrinology
CP-66948 is a histamine H2-receptor antagonist with gastric antisecretory activity and mucosal protective properties.

HY-47599

WAY-639418	Drug Derivative	Others
WAY-639418 is an active molecule for the study of amyloid diseases and synucleinopathies.

HY-162821

LI-3948	IPK Superfamily	Neurological Disease
IP6K-IN-2 (compound 29c) is an orally bioavailable and blood-brain barrier permeable IP6K inhibitor (IC₅₀: 15.8 nM) that can be used in the study of central nervous system diseases .

HY-R03354

*mmu-miR-6348* mimic**	MicroRNA	Cancer
mmu-miR-6348 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-6348 mimic mmu-miR-6348 mimic

HY-R03401

*mmu-miR-6394* mimic**	MicroRNA	Cancer
mmu-miR-6394 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-6394 mimic mmu-miR-6394 mimic

HY-106027

Romazarit RO 31-3948	PPAR	Metabolic Disease Inflammation/Immunology
Romazarit (RO 31-3948) is an anti-inflammatory agent with antirheumatic effect. Romazarit exhibits PPARα agonist activity. Romazarit (30 mg/kg) inhibits the development of hindpaw inflammation in an adjuvant arthritis model .

HY-R03622

*mmu-miR-6948-5p mimic*	MicroRNA	Cancer
mmu-miR-6948-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-6948-5p mimic mmu-miR-6948-5p mimic

HY-R03621

*mmu-miR-6948-3p mimic*	MicroRNA	Cancer
mmu-miR-6948-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-6948-3p mimic mmu-miR-6948-3p mimic

HY-RI03621

*mmu-miR-6948-3p inhibitor*	MicroRNA	Cancer
mmu-miR-6948-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-6948-3p inhibitor mmu-miR-6948-3p inhibitor

HY-RI03354A

*mmu-miR-6348* antagomir**	MicroRNA	Cancer
mmu-miR-6348 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-6348 antagomir mmu-miR-6348 antagomir

HY-RI03401

*mmu-miR-6394* inhibitor**	MicroRNA	Cancer
mmu-miR-6394 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-6394 inhibitor mmu-miR-6394 inhibitor

HY-RI03405

*mmu-miR-6398* inhibitor**	MicroRNA	Cancer
mmu-miR-6398 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-6398 inhibitor mmu-miR-6398 inhibitor

HY-RI03405A

*mmu-miR-6398* antagomir**	MicroRNA	Cancer
mmu-miR-6398 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-6398 antagomir mmu-miR-6398 antagomir

HY-R03405

*mmu-miR-6398* mimic**	MicroRNA	Cancer
mmu-miR-6398 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-6398 mimic mmu-miR-6398 mimic

HY-RI03401A

*mmu-miR-6394* antagomir**	MicroRNA	Cancer
mmu-miR-6394 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-6394 antagomir mmu-miR-6394 antagomir

HY-R03354A

*mmu-miR-6348* agomir**	MicroRNA	Cancer
mmu-miR-6348 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-6348 agomir mmu-miR-6348 agomir

HY-R03401A

*mmu-miR-6394* agomir**	MicroRNA	Cancer
mmu-miR-6394 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-6394 agomir mmu-miR-6394 agomir

HY-RI03354

*mmu-miR-6348* inhibitor**	MicroRNA	Cancer
mmu-miR-6348 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-6348 inhibitor mmu-miR-6348 inhibitor

HY-R03405A

*mmu-miR-6398* agomir**	MicroRNA	Cancer
mmu-miR-6398 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-6398 agomir mmu-miR-6398 agomir

HY-RI03622

*mmu-miR-6948-5p inhibitor*	MicroRNA	Cancer
mmu-miR-6948-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-6948-5p inhibitor mmu-miR-6948-5p inhibitor

HY-RI03621A

*mmu-miR-6948-3p antagomir*	MicroRNA	Cancer
mmu-miR-6948-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-6948-3p antagomir mmu-miR-6948-3p antagomir

HY-R03622A

*mmu-miR-6948-5p agomir*	MicroRNA	Cancer
mmu-miR-6948-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-6948-5p agomir mmu-miR-6948-5p agomir

HY-R03621A

*mmu-miR-6948-3p agomir*	MicroRNA	Cancer
mmu-miR-6948-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-6948-3p agomir mmu-miR-6948-3p agomir

HY-RI03622A

*mmu-miR-6948-5p antagomir*	MicroRNA	Cancer
mmu-miR-6948-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-6948-5p antagomir mmu-miR-6948-5p antagomir

Host:	Mouse (2) Rabbit (4)
Reactivity:	Human (6) Rat (3) Mouse (5) Monkey (1)
Application:	IHC-P (2) ICC/IF (2) IF-Tissue (2) IP (1) IHC-F (2) WB (6) FC (2) ELISA (2)
Isotype:	IgG (4) IgG2a (2)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (5) Recombinant (1)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84251

	SDHA Antibody (YA3948) FP; PGL5; SDH1; SDH2; SDHF; CMD1GG; MC2DN1; NDAXOA	WB, ICC/IF, FC, ELISA	Human, Mouse
	SDHA Antibody (YA3948) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SDHA.

HY-P84251A

	SDHA Antibody (YA3948)(PBS only) FP; PGL5; SDH1; SDH2; SDHF; CMD1GG; MC2DN1; NDAXOA	WB, ICC/IF, FC, ELISA	Human, Mouse
	SDHA Antibody (YA3948) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SDHA.

HY-P86706

	CD105 Antibody (YA6398) END; Endoglin; ENG; FLJ41744; HHT1; ORW; ORW1; Osler Rendu Weber syndrome 1; RP11 228B15.2; CD 105; CD105 antigen; EGLN_HUMAN; AI528660; AI662476; S-endoglin; SN6.	WB	Human
	CD105 Antibody (YA6398) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD105.

HY-P86702

	Neurofilament/NF-L Antibody (YA6394) Neurofilament L; Neurofilament 68; Neurofilament triplet L; 70 kD Neurofilament Light; 68kDa neurofilament protein; CMT 1F; CMT 2E; CMT1F; CMT2E; FLJ53642; Light molecular weight neurofilament protein; NEFL; Neurofilament light; Neurofilament light polypeptide 68kDa; Neurofilament light polypeptide; Neurofilament protein, light chain; Neurofilament subunit NF L; Neurofilament triplet L protein; NF 68; NF L; NF68; NFL; NFL_HUMAN.	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse, Rat
	Neurofilament/NF-L Antibody (YA6394) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Neurofilament/NF-L.

HY-P87265

	NDUFA9 Antibody (YA6948) CI-39kD antibody; Complex I subunit NDUFA9 antibody; Complex I-39kD antibody; mitochondrial antibody; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9 antibody; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9 mitochondrial antibody; NADH Ubiquinone Oxidoreductase 1 alpha subcomplex 9 antibody; NADH-ubiquinone oxidoreductase 39 kDa subunit antibody; NDUA9_HUMAN antibody; NDUFA9 antibody	WB, IP	Human, Mouse, Rat, Monkey
	NDUFA9 Antibody (YA6948) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NDUFA9.

HY-P86656

	MMP-9 Antibody (YA6348) Matrix metalloproteinase-9 precursor; MMP-9; MMP9; MMP 9; 92 kDa type IV; Collagenase; 92 kDa gelatinase; Gelatinase B; GELB; MMP9_HUMAN; 82 kDa matrix metalloproteinase-9; 92 kDa type IV collagenase; CLG 4B; CLG-4B; CLG4B; Collagenase Type 4 beta; Collagenase Type-4 beta; Collagenase type IV 92 KD; Collagenase type IV 92 KD; EC 3.4.24.35; Gelatinase 92 KD; Gelatinase 92 KD; Gelatinase beta; Gelatinase-beta; GelatinaseB; GELB; Macrophage gelatinase; MANDP2; Matrix metallopeptidase 9(gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); Matrix Metalloproteinase 9; Type V collagenase.	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse, Rat
	MMP-9 Antibody (YA6348) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MMP-9.

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Cat. No.	Product Name		Classification

HY-R03354

*mmu-miR-6348* mimic**		MicroRNAs miRNA mimics
mmu-miR-6348 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03401

*mmu-miR-6394* mimic**		MicroRNAs miRNA mimics
mmu-miR-6394 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03622

*mmu-miR-6948-5p mimic*		MicroRNAs miRNA mimics
mmu-miR-6948-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03621

*mmu-miR-6948-3p mimic*		MicroRNAs miRNA mimics
mmu-miR-6948-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI03621

*mmu-miR-6948-3p inhibitor*		MicroRNAs miRNA inhibitors
mmu-miR-6948-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03354A

*mmu-miR-6348* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-6348 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03401

*mmu-miR-6394* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-6394 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03405

*mmu-miR-6398* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-6398 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03405A

*mmu-miR-6398* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-6398 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03405

*mmu-miR-6398* mimic**		MicroRNAs miRNA mimics
mmu-miR-6398 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI03401A

*mmu-miR-6394* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-6394 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03354A

*mmu-miR-6348* agomir**		MicroRNAs miRNA agomirs
mmu-miR-6348 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03401A

*mmu-miR-6394* agomir**		MicroRNAs miRNA agomirs
mmu-miR-6394 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03354

*mmu-miR-6348* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-6348 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03405A

*mmu-miR-6398* agomir**		MicroRNAs miRNA agomirs
mmu-miR-6398 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03622

*mmu-miR-6948-5p inhibitor*		MicroRNAs miRNA inhibitors
mmu-miR-6948-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03621A

*mmu-miR-6948-3p antagomir*		MicroRNAs miRNA antagomirs
mmu-miR-6948-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03622A

*mmu-miR-6948-5p agomir*		MicroRNAs miRNA agomirs
mmu-miR-6948-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03621A

*mmu-miR-6948-3p agomir*		MicroRNAs miRNA agomirs
mmu-miR-6948-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03622A

*mmu-miR-6948-5p antagomir*		MicroRNAs miRNA antagomirs
mmu-miR-6948-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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