Zbtb18 - zinc finger and BTB domain containing 18 Gene

Also Known as Rp58; Zfp238; Znf238

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64619

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and skeletal muscle tissue development. Predicted to act upstream of or within several processes, including in utero embryonic development; nervous system development; and regulation of cell division. Predicted to be located in heterochromatin and nuclear speck. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 22. Orthologous to human ZBTB18 (zinc finger and BTB domain containing 18). [provided by Alliance of Genome Resources, Apr 2022]

Zbtb18 Products (2)

mRNA Protein Name
NM_001401285.1 NP_001388214.1 zinc finger and BTB domain-containing protein 18 isoform 2
NM_022678.2 NP_073169.2 zinc finger and BTB domain-containing protein 18 isoform 1
Protein Preferred Names Protein Names

zinc finger and BTB domain-containing protein 18

  • 58 kDa repressor protein

  • rRP58

  • transcriptional repressor RP58

  • zinc finger protein 238

Orthologs Information

Species Symbol Source ID
Homo sapiens Zbtb18 NCBI NCBI:10472