2. Gene
  3. Zbtb18 - zinc finger and BTB domain containing 18 Gene

Zbtb18 - zinc finger and BTB domain containing 18 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Rp58; Zfp238; Znf238

Gene ID: 64619 | Gene type: protein coding

About Zbtb18

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and skeletal muscle tissue development. Predicted to act upstream of or within several processes, including in utero embryonic development; nervous system development; and regulation of cell division. Predicted to be located in heterochromatin and nuclear speck. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 22. Orthologous to human ZBTB18 (zinc finger and BTB domain containing 18). [provided by Alliance of Genome Resources, Apr 2022]

Zbtb18 Products(2)

mRNA Protein Name
NM_001401285.1 NP_001388214.1 zinc finger and BTB domain-containing protein 18 isoform 2
NM_022678.2 NP_073169.2 zinc finger and BTB domain-containing protein 18 isoform 1
Protein Preferred Names Protein Names

zinc finger and BTB domain-containing protein 18

58 kDa repressor protein

rRP58

transcriptional repressor RP58

zinc finger protein 238

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15966 ZBTB18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zbtb18 NCBI NCBI:10472