2. Gene
  3. ARL3 - Arl3 ADP ribosylation factor like GTPase 3 Gene

ARL3 - Arl3 ADP ribosylation factor like GTPase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 64664 | Gene type: protein coding

About ARL3

Summary

Enables GDP binding activity and GTP binding activity. Predicted to be involved in several processes, including Golgi to plasma membrane transport; protein localization to ciliary membrane; and small GTPase mediated signal transduction. Predicted to act upstream of or within intraciliary transport; post-Golgi vesicle-mediated transport; and smoothened signaling pathway. Predicted to be located in several cellular components, including cytoskeleton; midbody; and photoreceptor connecting cilium. Predicted to be active in cytoplasm and microtubule Cytoskeleton. Human ortholog(s) of this gene implicated in Joubert syndrome and retinitis pigmentosa 83. Orthologous to human ARL3 (ADP ribosylation factor like GTPase 3). [provided by Alliance of Genome Resources, Apr 2022]

ARL3 Products(1)

mRNA Protein Name
NM_022700.2 NP_073191.1 ADP-ribosylation factor-like protein 3
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables GDP binding IDA
IDA: Inferred from direct assay
8034651 RGD
enables GTP binding IDA
IDA: Inferred from direct assay
8034651 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ADP-ribosylation factor-like protein 3

ADP-ribosylation factor-like 3

ADP-ribosylation-like 3

ARD3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00987 ARL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ARL3 NCBI NCBI:403