2. Gene
  3. Pcdh8 - protocadherin 8 Gene

Pcdh8 - protocadherin 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Arcadlin

Gene ID: 64865 | Gene type: protein coding

About Pcdh8

Summary

Predicted to enable calcium ion binding activity. Involved in chemical synaptic transmission; modulation of chemical synaptic transmission; and regulation of synaptic membrane adhesion. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is integral component of postsynaptic membrane. Orthologous to human PCDH8 (protocadherin 8). [provided by Alliance of Genome Resources, Apr 2022]

Pcdh8 Products(2)

mRNA Protein Name
NM_001411975.1 NP_001398904.1 protocadherin-8 isoform 1 precursor
NM_022868.2 NP_074059.2 protocadherin-8 isoform 2 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in chemical synaptic transmission IDA
IDA: Inferred from direct assay
10383464 RGD
involved in modulation of chemical synaptic transmission EXP
EXP: Inferred from Experiment
10383464 RGD
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
10383464 RGD
involved in regulation of synaptic membrane adhesion IDA
IDA: Inferred from direct assay
17988630 RGD
involved in regulation of synaptic membrane adhesion IMP
IMP: Inferred from mutant phenotype
17988630 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in Schaffer collateral - CA1 synapse EXP
EXP: Inferred from Experiment
10383464 RGD
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
10383464 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17988630 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
17988630 RGD
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
17988630 RGD
is active in synapse IDA
IDA: Inferred from direct assay
10383464 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protocadherin-8

activity-regulated cadherin-like protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10131 PCDH8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcdh8 NCBI NCBI:5100