Asb4 - ankyrin repeat and SOCS box-containing 4 Gene

Also Known as 8430401O13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 65255

Summary

Enables ubiquitin protein Ligase activity and ubiquitin protein Ligase binding activity. Involved in positive regulation of vasculogenesis and protein autoubiquitination. Part of Cul2-RING ubiquitin Ligase complex and Cul5-RING ubiquitin Ligase complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; extraembryonic component; and limb. Used to study pre-eclampsia. Orthologous to human ASB4 (ankyrin repeat and SOCS box containing 4). [provided by Alliance of Genome Resources, Apr 2022]

Asb4 Products (2)

mRNA Protein Name
NM_001355662.1 NP_001342591.1 ankyrin repeat and SOCS box protein 4
NM_023048.5 NP_075535.1 ankyrin repeat and SOCS box protein 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
17636018 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
17636018 MGI
enables ubiquitin protein ligase binding IDA
IDA: Inferred from direct assay
17636018 MGI
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
17636018 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of vasculogenesis IDA
IDA: Inferred from direct assay
17636018 MGI
involved in protein autoubiquitination IDA
IDA: Inferred from direct assay
17636018 MGI
Cellular Component GO Annotation Evidence References Source
part of Cul2-RING ubiquitin ligase complex IDA
IDA: Inferred from direct assay
17636018 MGI
part of Cul5-RING ubiquitin ligase complex IDA
IDA: Inferred from direct assay
17636018 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ankyrin repeat and SOCS box protein 4

  • ASB-4

  • ankyrin repeat and SOCS box-containing protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01069 ASB4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Asb4 NCBI NCBI:51666