2. Gene
  3. Asb4 - ankyrin repeat and SOCS box-containing 4 Gene

Asb4 - ankyrin repeat and SOCS box-containing 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 8430401O13Rik

Gene ID: 65255 | Gene type: protein coding

About Asb4

Summary

Enables ubiquitin protein Ligase activity and ubiquitin protein Ligase binding activity. Involved in positive regulation of vasculogenesis and protein autoubiquitination. Part of Cul2-RING ubiquitin Ligase complex and Cul5-RING ubiquitin Ligase complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; extraembryonic component; and limb. Used to study pre-eclampsia. Orthologous to human ASB4 (ankyrin repeat and SOCS box containing 4). [provided by Alliance of Genome Resources, Apr 2022]

Asb4 Products(2)

mRNA Protein Name
NM_001355662.1 NP_001342591.1 ankyrin repeat and SOCS box protein 4
NM_023048.5 NP_075535.1 ankyrin repeat and SOCS box protein 4
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
17636018 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
17636018 MGI
enables ubiquitin protein ligase binding IDA
IDA: Inferred from direct assay
17636018 MGI
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
17636018 MGI
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of vasculogenesis IDA
IDA: Inferred from direct assay
17636018 MGI
involved in protein autoubiquitination IDA
IDA: Inferred from direct assay
17636018 MGI
Cellular Component GO Annotation Evidence Reference Source
part of Cul2-RING ubiquitin ligase complex IDA
IDA: Inferred from direct assay
17636018 MGI
part of Cul5-RING ubiquitin ligase complex IDA
IDA: Inferred from direct assay
17636018 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ankyrin repeat and SOCS box protein 4

ASB-4

ankyrin repeat and SOCS box-containing protein 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01069 ASB4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Asb4 NCBI NCBI:51666