2. Gene
  3. ARHGEF9 - Arhgef9 Cdc42 guanine nucleotide exchange factor 9 Gene

ARHGEF9 - Arhgef9 Cdc42 guanine nucleotide exchange factor 9 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 66013 | Gene type: protein coding

About ARHGEF9

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in receptor clustering. Located in cell cortex. Is active in GABA-ergic synapse; glycinergic synapse; and postsynaptic specialization. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 8. Orthologous to human ARHGEF9 (Cdc42 guanine nucleotide exchange factor 9). [provided by Alliance of Genome Resources, Apr 2022]

ARHGEF9 Products(2)

mRNA Protein Name
NM_001393743.1 NP_001380672.1 rho guanine nucleotide exchange factor 9 isoform 2
NM_023957.2 NP_076447.2 rho guanine nucleotide exchange factor 9 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10607391 RGD
Biological Process GO Annotation Evidence Reference Source
involved in receptor clustering IDA
IDA: Inferred from direct assay
10607391 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
21681748 RGD
located in cell cortex IDA
IDA: Inferred from direct assay
10607391 RGD
is active in glycinergic synapse IDA
IDA: Inferred from direct assay
21681748 RGD
is active in postsynaptic specialization IDA
IDA: Inferred from direct assay
21681748 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho guanine nucleotide exchange factor 9

Cdc42 guanine nucleotide exchange factor (GEF) 9

collybistin I

rac/Cdc42 guanine nucleotide exchange factor 9

rho guanine nucleotide exchange factor 9-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00965 ARHGEF9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ARHGEF9 NCBI NCBI:23229