ARHGEF9 - Arhgef9 Cdc42 guanine nucleotide exchange factor 9 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 66013

Summary

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in receptor clustering. Located in cell cortex. Is active in GABA-ergic synapse; glycinergic synapse; and postsynaptic specialization. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 8. Orthologous to human ARHGEF9 (Cdc42 guanine nucleotide exchange factor 9). [provided by Alliance of Genome Resources, Apr 2022]

ARHGEF9 Products (2)

mRNA Protein Name
NM_001393743.1 NP_001380672.1 rho guanine nucleotide exchange factor 9 isoform 2
NM_023957.2 NP_076447.2 rho guanine nucleotide exchange factor 9 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10607391 RGD
Biological Process GO Annotation Evidence References Source
involved in receptor clustering IDA
IDA: Inferred from direct assay
10607391 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
21681748 RGD
located in cell cortex IDA
IDA: Inferred from direct assay
10607391 RGD
is active in glycinergic synapse IDA
IDA: Inferred from direct assay
21681748 RGD
is active in postsynaptic specialization IDA
IDA: Inferred from direct assay
21681748 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho guanine nucleotide exchange factor 9

  • Cdc42 guanine nucleotide exchange factor (GEF) 9

  • collybistin I

  • rac/Cdc42 guanine nucleotide exchange factor 9

  • rho guanine nucleotide exchange factor 9-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00965 ARHGEF9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ARHGEF9 NCBI NCBI:23229